microRNA-124 inhibits bone metastasis of breast cancer by repressing Interleukin-11

microRNA-124 inhibits bone metastasis of breast cancer by repressing Interleukin-11

Abstract Background Most patients with breast cancer in advanced stages of the disease suffer from bone metastases which lead to fractures and nerve compression syndromes. microRNA dysregulation is an important event in the metastases of breast cancer to bone. microRNA-124 (miR-124) has been proved...

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Bibliographic Details
Main Authors: Wei-Luo Cai, Wen-Ding Huang, Bo Li, Tian-Rui Chen, Zhen-Xi Li, Cheng-Long Zhao, Heng-Yu Li, Yan-Mei Wu, Wang-Jun Yan, Jian-Ru Xiao
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Molecular Cancer
Subjects:
Breast cancer
Bone metastasis
miR-124
IL-11
Bone microenvironment
Online Access:http://link.springer.com/article/10.1186/s12943-017-0746-0

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