$Skeletal muscle phenotypic switching in heart failure with preserved ejection fraction$

Skeletal muscle phenotypic switching in heart failure with preserved ejection fraction

BackgroundSkeletal muscle (SkM) phenotypic switching is associated with exercise intolerance in heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF have decreased type-1 oxidative fibers and mitochondrial dysfunction, indicative of impaired oxidative capacity. The SAUNA (SAlt...

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Bibliographic Details
Main Authors:	Eng Leng Saw, Louis Dominic Werner, Payman Zamani, Julio A. Chirinos, María Valero-Muñoz, Flora Sam
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	heart failure with preserved ejection fraction exercise intolerance skeletal muscle oxidative metabolism fibers atrophy
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.1016452/full

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