Skeletal muscle phenotypic switching in heart failure with preserved ejection fraction
BackgroundSkeletal muscle (SkM) phenotypic switching is associated with exercise intolerance in heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF have decreased type-1 oxidative fibers and mitochondrial dysfunction, indicative of impaired oxidative capacity. The SAUNA (SAlt...
Main Authors: | Eng Leng Saw, Louis Dominic Werner, Payman Zamani, Julio A. Chirinos, María Valero-Muñoz, Flora Sam |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
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Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1016452/full |
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