D-Mannoside FimH Inhibitors as Non-Antibiotic Alternatives for Uropathogenic <i>Escherichia coli</i>

D-Mannoside FimH Inhibitors as Non-Antibiotic Alternatives for Uropathogenic <i>Escherichia coli</i>

FimH is a type I fimbria of uropathogenic <i>Escherichia coli</i> (UPEC), recognized for its ability to adhere and infect epithelial urinary tissue. Due to its role in the virulence of UPEC, several therapeutic strategies have focused on the study of FimH, including vaccines, mannosides,...

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Bibliographic Details
Main Authors: Alfredo Montes-Robledo, Rosa Baldiris-Avila, Johan Fabian Galindo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
UPEC
FimH
molecular dynamics
virulence factors
antibiotic resistance
Online Access:https://www.mdpi.com/2079-6382/10/9/1072

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