Dynamics of HIV-1 Gag Processing as Revealed by Fluorescence Lifetime Imaging Microscopy and Single Virus Tracking

Dynamics of HIV-1 Gag Processing as Revealed by Fluorescence Lifetime Imaging Microscopy and Single Virus Tracking

The viral polyprotein Gag plays a central role for HIV-1 assembly, release and maturation. Proteolytic processing of Gag by the viral protease is essential for the structural rearrangements that mark the transition from immature to mature, infectious viruses. The timing and kinetics of Gag processin...

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Bibliographic Details
Main Authors: Chen Qian, Annica Flemming, Barbara Müller, Don C. Lamb
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
HIV
maturation
gag processing
fluorescence lifetime
single virus tracking
Online Access:https://www.mdpi.com/1999-4915/14/2/340

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