The mRNA-1273 Vaccine Induces Cross-Variant Antibody Responses to SARS-CoV-2 With Distinct Profiles in Individuals With or Without Pre-Existing Immunity

The mRNA-1273 Vaccine Induces Cross-Variant Antibody Responses to SARS-CoV-2 With Distinct Profiles in Individuals With or Without Pre-Existing Immunity

mRNA-based vaccines effectively induce protective neutralizing antibodies against SARS-CoV-2, the etiological agent of COVID-19. Yet, the kinetics and compositional patterns of vaccine-induced antibody responses to the original strain and emerging variants of concern remain largely unknown. Here we...

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Bibliographic Details
Main Authors: Sonia Tejedor Vaquero, Leire de Campos-Mata, José María Ramada, Pilar Díaz, Juan Navarro-Barriuso, Clara Ribas-Llaurado, Natalia Rodrigo Melero, Carlo Carolis, Andrea Cerutti, Ramon Gimeno, Giuliana Magri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
humoral immunity
antibody subclasses
COVID-19
variants of concern
mRNA vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.737083/full

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