Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L.
In order to optimize the extraction process of total flavonoids of Sedum aizoon L. (TFS) and study its anti-oxidant and anti-fatigue activities. This study used single-factor and orthogonal tests to optimize the optimal extraction conditions for TFS and evaluate its anti-oxidant activity in vitro. T...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Journal of Agriculture and Food Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666154323000674 |
| _version_ | 1827943668736065536 |
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| author | Shuang Liu Muyao Wang Yibin Xing Xueru Wang Chengbi Cui |
| author_facet | Shuang Liu Muyao Wang Yibin Xing Xueru Wang Chengbi Cui |
| author_sort | Shuang Liu |
| collection | DOAJ |
| description | In order to optimize the extraction process of total flavonoids of Sedum aizoon L. (TFS) and study its anti-oxidant and anti-fatigue activities. This study used single-factor and orthogonal tests to optimize the optimal extraction conditions for TFS and evaluate its anti-oxidant activity in vitro. The anti-fatigue activity of mice was evaluated by measuring their pole-climbing time and exhausted swimming time after mice given gavage for 30 days. Hepatic glycogen (HG)/Muscle glycogen (MG), Lactic acid (LD), Lactate dehydrogenase (LDH), Blood urea nitrogen (BUN), Malondialdehyde (MDA), Superoxide dismutase (SOD), Glutathione peroxidase (GSH-Px), and Catalase (CAT) were measured to explore possible causes of anti-fatigue. The results showed that TFS has good anti-oxidant activity in vitro and in vivo, and had significant anti-fatigue effects in mice. Therefore, TFS is thought to have an anti-fatigue effect by improving the body's oxidative stress response. |
| first_indexed | 2024-03-13T10:18:52Z |
| format | Article |
| id | doaj.art-7b25b63af92e4110af745835d957a551 |
| institution | Directory Open Access Journal |
| issn | 2666-1543 |
| language | English |
| last_indexed | 2024-03-13T10:18:52Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Agriculture and Food Research |
| spelling | doaj.art-7b25b63af92e4110af745835d957a5512023-05-21T04:35:39ZengElsevierJournal of Agriculture and Food Research2666-15432023-06-0112100560Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L.Shuang Liu0Muyao Wang1Yibin Xing2Xueru Wang3Chengbi Cui4Food Science and Engineering, Convergence College, Yanbian University, Yanji, 133000, ChinaDepartment of Food Processing and Safety, College of Agricultural, Yanbian University, Yanji, 133000, ChinaDepartment of Food Processing and Safety, College of Agricultural, Yanbian University, Yanji, 133000, ChinaFood Science and Engineering, Convergence College, Yanbian University, Yanji, 133000, ChinaFood Science and Engineering, Convergence College, Yanbian University, Yanji, 133000, China; Department of Food Processing and Safety, College of Agricultural, Yanbian University, Yanji, 133000, China; Corresponding author. Convergence College, Yanbian University, Yanji, 133002, China.In order to optimize the extraction process of total flavonoids of Sedum aizoon L. (TFS) and study its anti-oxidant and anti-fatigue activities. This study used single-factor and orthogonal tests to optimize the optimal extraction conditions for TFS and evaluate its anti-oxidant activity in vitro. The anti-fatigue activity of mice was evaluated by measuring their pole-climbing time and exhausted swimming time after mice given gavage for 30 days. Hepatic glycogen (HG)/Muscle glycogen (MG), Lactic acid (LD), Lactate dehydrogenase (LDH), Blood urea nitrogen (BUN), Malondialdehyde (MDA), Superoxide dismutase (SOD), Glutathione peroxidase (GSH-Px), and Catalase (CAT) were measured to explore possible causes of anti-fatigue. The results showed that TFS has good anti-oxidant activity in vitro and in vivo, and had significant anti-fatigue effects in mice. Therefore, TFS is thought to have an anti-fatigue effect by improving the body's oxidative stress response.http://www.sciencedirect.com/science/article/pii/S2666154323000674Sedum aizoon L.Total flavonoidsAntioxidant activityAnti-fatigueOxidative stress |
| spellingShingle | Shuang Liu Muyao Wang Yibin Xing Xueru Wang Chengbi Cui Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L. Journal of Agriculture and Food Research Sedum aizoon L. Total flavonoids Antioxidant activity Anti-fatigue Oxidative stress |
| title | Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L. |
| title_full | Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L. |
| title_fullStr | Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L. |
| title_full_unstemmed | Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L. |
| title_short | Anti-oxidation and anti-fatigue effects of the total flavonoids of Sedum aizoon L. |
| title_sort | anti oxidation and anti fatigue effects of the total flavonoids of sedum aizoon l |
| topic | Sedum aizoon L. Total flavonoids Antioxidant activity Anti-fatigue Oxidative stress |
| url | http://www.sciencedirect.com/science/article/pii/S2666154323000674 |
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