Vaccination of cattle with the Babesia bovis sexual-stage protein HAP2 abrogates parasite transmission by Rhipicephalus microplus ticks

Abstract The apicomplexan parasite Babesia bovis is responsible for bovine babesiosis, a poorly controlled tick-borne disease of global impact. The widely conserved gametocyte protein HAPLESS2/GCS1 (HAP2) is uniquely expressed on the surface of B. bovis sexual stage parasites and is a candidate for...

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Bibliographic Details
Main Authors: Marta G. Silva, Reginaldo G. Bastos, Jacob M. Laughery, Heba F. Alzan, Vignesh A. Rathinasamy, Brian M. Cooke, Carlos E. Suarez
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00741-8