Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019
Abstract Background Lung cancer is one of the leading cancers, with a high burden worldwide. As a developing country, Iran is facing with population growth, widespread tobacco use, demographic and epidemiologic changes, and environmental exposures, which lead to cancers becoming a severe concern of...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-12-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.4792 |
| _version_ | 1811188101120262144 |
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| author | Zahra Shokri Varniab Yeganeh Sharifnejad Tehrani Ashkan Pourabhari Langroudi Sina Azadnajafabad Negar Rezaei Mohammad‐Mahdi Rashidi Zahra Esfahani Mohammad‐Reza Malekpour Erfan Ghasemi Azin Ghamari Arezou Dilmaghani‐Marand Sahar Mohammadi Fateh Alireza Namazi Shabestari Bagher Larijani Farshad Farzadfar |
| author_facet | Zahra Shokri Varniab Yeganeh Sharifnejad Tehrani Ashkan Pourabhari Langroudi Sina Azadnajafabad Negar Rezaei Mohammad‐Mahdi Rashidi Zahra Esfahani Mohammad‐Reza Malekpour Erfan Ghasemi Azin Ghamari Arezou Dilmaghani‐Marand Sahar Mohammadi Fateh Alireza Namazi Shabestari Bagher Larijani Farshad Farzadfar |
| author_sort | Zahra Shokri Varniab |
| collection | DOAJ |
| description | Abstract Background Lung cancer is one of the leading cancers, with a high burden worldwide. As a developing country, Iran is facing with population growth, widespread tobacco use, demographic and epidemiologic changes, and environmental exposures, which lead to cancers becoming a severe concern of public health in Iran. We aimed to examine the burden of lung cancer and its risk factors in Iran. Methods We utilized the Global Burden of Disease 2019 data and analyzed the total burden of the lung cancer and seven related risk factors by sex, age at national and sub‐national levels from 1990 to 2019. Results The lung cancer age‐standardized death rate increased from 11.8 (95% Uncertainty Interval: 9.7–14.4) to 12.9 (11.9–13.9) per 100,000 between 1990 and 2019. This increase was among women from 5 (4.2–7.1) to 8 (7.2–8.8) per 100,000; in contrast, there was a decline among men from 18.5 (14.8–22.6) to 17.8 (16.2–19.4) per 100,000. The burden of lung cancer is concentrated in the advanced age groups. Smoking with 53.5% of total attributable deaths (51.0%–55.9%) was the leading risk factor. At the provincial level, there was a wide range between the lowest and highest, from 8.3 (7.0–10.0) to 19.1 (16.4–22.0) per 100,000 population in the incidence rate and from 8.7 (7.3–10.3) to 20.6 (17.7–24.0) per 100,000 population in mortality rate, respectively in Tehran and West Azerbaijan provinces in 2019. Conclusion The increasing trend of lung cancer burden among the entire Iranian population, the inter‐provincial disparities, and the significant rise in burden of this cancer in women necessitate the urgent implementation and development of policies to prevent and manage lung cancer burden and strategies to reduce exposure to risk factors. |
| first_indexed | 2024-04-11T14:14:42Z |
| format | Article |
| id | doaj.art-7b2ea0e51eae43c6a7e0cb89e2f9cb3f |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-04-11T14:14:42Z |
| publishDate | 2022-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-7b2ea0e51eae43c6a7e0cb89e2f9cb3f2022-12-22T04:19:36ZengWileyCancer Medicine2045-76342022-12-0111234624464010.1002/cam4.4792Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019Zahra Shokri Varniab0Yeganeh Sharifnejad Tehrani1Ashkan Pourabhari Langroudi2Sina Azadnajafabad3Negar Rezaei4Mohammad‐Mahdi Rashidi5Zahra Esfahani6Mohammad‐Reza Malekpour7Erfan Ghasemi8Azin Ghamari9Arezou Dilmaghani‐Marand10Sahar Mohammadi Fateh11Alireza Namazi Shabestari12Bagher Larijani13Farshad Farzadfar14Non‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranDepartment of Geriatric Medicine, School of Medicine Tehran University of Medical Sciences Tehran IranEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranAbstract Background Lung cancer is one of the leading cancers, with a high burden worldwide. As a developing country, Iran is facing with population growth, widespread tobacco use, demographic and epidemiologic changes, and environmental exposures, which lead to cancers becoming a severe concern of public health in Iran. We aimed to examine the burden of lung cancer and its risk factors in Iran. Methods We utilized the Global Burden of Disease 2019 data and analyzed the total burden of the lung cancer and seven related risk factors by sex, age at national and sub‐national levels from 1990 to 2019. Results The lung cancer age‐standardized death rate increased from 11.8 (95% Uncertainty Interval: 9.7–14.4) to 12.9 (11.9–13.9) per 100,000 between 1990 and 2019. This increase was among women from 5 (4.2–7.1) to 8 (7.2–8.8) per 100,000; in contrast, there was a decline among men from 18.5 (14.8–22.6) to 17.8 (16.2–19.4) per 100,000. The burden of lung cancer is concentrated in the advanced age groups. Smoking with 53.5% of total attributable deaths (51.0%–55.9%) was the leading risk factor. At the provincial level, there was a wide range between the lowest and highest, from 8.3 (7.0–10.0) to 19.1 (16.4–22.0) per 100,000 population in the incidence rate and from 8.7 (7.3–10.3) to 20.6 (17.7–24.0) per 100,000 population in mortality rate, respectively in Tehran and West Azerbaijan provinces in 2019. Conclusion The increasing trend of lung cancer burden among the entire Iranian population, the inter‐provincial disparities, and the significant rise in burden of this cancer in women necessitate the urgent implementation and development of policies to prevent and manage lung cancer burden and strategies to reduce exposure to risk factors.https://doi.org/10.1002/cam4.4792global burden of diseaseIranlung cancer |
| spellingShingle | Zahra Shokri Varniab Yeganeh Sharifnejad Tehrani Ashkan Pourabhari Langroudi Sina Azadnajafabad Negar Rezaei Mohammad‐Mahdi Rashidi Zahra Esfahani Mohammad‐Reza Malekpour Erfan Ghasemi Azin Ghamari Arezou Dilmaghani‐Marand Sahar Mohammadi Fateh Alireza Namazi Shabestari Bagher Larijani Farshad Farzadfar Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019 Cancer Medicine global burden of disease Iran lung cancer |
| title | Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019 |
| title_full | Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019 |
| title_fullStr | Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019 |
| title_full_unstemmed | Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019 |
| title_short | Estimates of incidence, prevalence, mortality, and disability‐adjusted life years of lung cancer in Iran, 1990–2019: A systematic analysis from the global burden of disease study 2019 |
| title_sort | estimates of incidence prevalence mortality and disability adjusted life years of lung cancer in iran 1990 2019 a systematic analysis from the global burden of disease study 2019 |
| topic | global burden of disease Iran lung cancer |
| url | https://doi.org/10.1002/cam4.4792 |
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