Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons

Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons

Abstract Background Violacein is a deep violet compound that is produced by a number of bacterial species. It is synthesized from tryptophan by a pathway that involves the sequential action of 5 different enzymes (encoded by genes vioA to vioE). Violacein has antibacterial, antiparasitic, and antivi...

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Bibliographic Details
Main Authors: Elizabeth Bilsland, Tatyana A. Tavella, Renata Krogh, Jamie E. Stokes, Annabelle Roberts, James Ajioka, David R. Spring, Adriano D. Andricopulo, Fabio T. M. Costa, Stephen G. Oliver
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Biotechnology
Subjects:
Violacein
Deoxyviolacein
Plasmodium falciparum
Trypanosoma cruzi
Synthetic operon
Antiparasitic
Online Access:http://link.springer.com/article/10.1186/s12896-018-0428-z

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