Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study
Background: India, with the highest number of tuberculosis (TB) cases in the world, is also facing epidemic growth in diabetes mellitus (DM). TB is curable while DM is a metabolic and incurable disease that if not controlled will affect the health status of a person. This study was conducted to asse...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Community Medicine |
| Subjects: | |
| Online Access: | http://www.ijcm.org.in/article.asp?issn=0970-0218;year=2023;volume=48;issue=1;spage=75;epage=81;aulast=Solanki |
| _version_ | 1797866572246679552 |
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| author | Harsha M Solanki Pooja N Ranpariya Rajesh K Chudasama |
| author_facet | Harsha M Solanki Pooja N Ranpariya Rajesh K Chudasama |
| author_sort | Harsha M Solanki |
| collection | DOAJ |
| description | Background: India, with the highest number of tuberculosis (TB) cases in the world, is also facing epidemic growth in diabetes mellitus (DM). TB is curable while DM is a metabolic and incurable disease that if not controlled will affect the health status of a person. This study was conducted to assess the health status and treatment outcome of TB with DM cases. Materials and Methods: We selected a total of 64 newly registered pulmonary TB (PTB) with DM cases from five tuberculosis units (TUs) in Rajkot city from October 2019 to December 2020. At the end of treatment, 64 cases were analyzed for treatment outcome and 56 cases (5 deaths; 3 lost to follow-up) were followed up to observe progression in health status. The information was collected in pretested proforma by interview. Results: There was a significant improvement in TB symptoms (cough, weight loss, weakness, anorexia, evening rise of temperature, dyspnea, chest pain, hemoptysis), DM symptoms (frequent urination, excessive thirst and hunger, tingling and numbness), symptoms of mental health (fatigue, sleep disturbance, negative emotions, socially inactive), and adverse drug reactions (ADRs) on consecutive visits (McNemar's test, P < 0.001) and at the end of treatment (Cochran's Q test, P < 0.001). Improvement of nutritional status was also found statistically significant on consecutive visits (Wilcoxon test, P < 0.001) and at the end of treatment (Friedman's test, P < 0.001). The cure rate was 82.8% and 4.7% of cases had completed treatment. Conclusion: At the end of treatment, there was a significant improvement in health status and treatment outcome; also good cure rate was reported among cases. |
| first_indexed | 2024-04-09T23:27:23Z |
| format | Article |
| id | doaj.art-7b36f2176db54f06aff48992f49e6ec5 |
| institution | Directory Open Access Journal |
| issn | 0970-0218 1998-3581 |
| language | English |
| last_indexed | 2024-04-09T23:27:23Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Community Medicine |
| spelling | doaj.art-7b36f2176db54f06aff48992f49e6ec52023-03-21T08:41:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Community Medicine0970-02181998-35812023-01-01481758110.4103/ijcm.ijcm_171_22Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal studyHarsha M SolankiPooja N RanpariyaRajesh K ChudasamaBackground: India, with the highest number of tuberculosis (TB) cases in the world, is also facing epidemic growth in diabetes mellitus (DM). TB is curable while DM is a metabolic and incurable disease that if not controlled will affect the health status of a person. This study was conducted to assess the health status and treatment outcome of TB with DM cases. Materials and Methods: We selected a total of 64 newly registered pulmonary TB (PTB) with DM cases from five tuberculosis units (TUs) in Rajkot city from October 2019 to December 2020. At the end of treatment, 64 cases were analyzed for treatment outcome and 56 cases (5 deaths; 3 lost to follow-up) were followed up to observe progression in health status. The information was collected in pretested proforma by interview. Results: There was a significant improvement in TB symptoms (cough, weight loss, weakness, anorexia, evening rise of temperature, dyspnea, chest pain, hemoptysis), DM symptoms (frequent urination, excessive thirst and hunger, tingling and numbness), symptoms of mental health (fatigue, sleep disturbance, negative emotions, socially inactive), and adverse drug reactions (ADRs) on consecutive visits (McNemar's test, P < 0.001) and at the end of treatment (Cochran's Q test, P < 0.001). Improvement of nutritional status was also found statistically significant on consecutive visits (Wilcoxon test, P < 0.001) and at the end of treatment (Friedman's test, P < 0.001). The cure rate was 82.8% and 4.7% of cases had completed treatment. Conclusion: At the end of treatment, there was a significant improvement in health status and treatment outcome; also good cure rate was reported among cases.http://www.ijcm.org.in/article.asp?issn=0970-0218;year=2023;volume=48;issue=1;spage=75;epage=81;aulast=Solankidiabetes mellitushealth statustreatment outcometuberculosis |
| spellingShingle | Harsha M Solanki Pooja N Ranpariya Rajesh K Chudasama Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study Indian Journal of Community Medicine diabetes mellitus health status treatment outcome tuberculosis |
| title | Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study |
| title_full | Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study |
| title_fullStr | Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study |
| title_full_unstemmed | Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study |
| title_short | Health status and treatment outcome of tuberculosis with diabetes mellitus cases, Rajkot City, Gujarat – A longitudinal study |
| title_sort | health status and treatment outcome of tuberculosis with diabetes mellitus cases rajkot city gujarat a longitudinal study |
| topic | diabetes mellitus health status treatment outcome tuberculosis |
| url | http://www.ijcm.org.in/article.asp?issn=0970-0218;year=2023;volume=48;issue=1;spage=75;epage=81;aulast=Solanki |
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