The use of adenoviral vectors in gene therapy and vaccine approaches

Abstract Adenovirus was first identified in the 1950s and since then this pathogenic group of viruses has been explored and transformed into a genetic transfer vehicle. Modification or deletion of few genes are necessary to transform it into a conditionally or non-replicative vector, creating a vers...

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Bibliographic Details
Main Authors: Natália Meneses Araújo, Ileana Gabriela Sanchez Rubio, Nicholas Pietro Agulha Toneto, Mirian Galliote Morale, Rodrigo Esaki Tamura
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2022-10-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572022000400108&tlng=en