Obstructive sleep apnea and the severity of coronary artery disease
Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2018-05-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/browse.php?a_code=A-10-755-2&slc_lang=en&sid=1 |
| _version_ | 1819034106315407360 |
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| author | Ali Vasheghani-Farahani Fatemeh Kazemnejad Khosro Sadeghniiat-Haghighi Soleil Saadat Parya Tavakoli poor Tahereh Yazdani Mohammad Alidoosti Vahid Ghasem Amooeian Haleh Ashraf |
| author_facet | Ali Vasheghani-Farahani Fatemeh Kazemnejad Khosro Sadeghniiat-Haghighi Soleil Saadat Parya Tavakoli poor Tahereh Yazdani Mohammad Alidoosti Vahid Ghasem Amooeian Haleh Ashraf |
| author_sort | Ali Vasheghani-Farahani |
| collection | DOAJ |
| description | Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and severity of atherosclerosis assessed by angiography.
Methods: This study included 337 patients undergoing diagnostic coronary angiography at Tehran Heart Center, Iran. The Gensini score was obtained from each patient for coronary angiogram, and OSA were assessed by using Multivariable apnea prediction (MAP) risk index on the day of cardiac catheterization. The Gensini scores increased in accordance with increases in the MAP value.
Results: The prevalence rates of three-vessel disease were 68.0% in OSA group and 32.0% in non-OSA group. The MAP index was the most significant independent determinant for the Gensini score.
Conclusions: The independent association between OSA and CAD, even after adjustment for traditional confounders, suggests that, OSA should be taken into account when considering risk factors for CAD. |
| first_indexed | 2024-12-21T07:28:27Z |
| format | Article |
| id | doaj.art-7b3bd6ba50524d4199ce88db870dc85c |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-12-21T07:28:27Z |
| publishDate | 2018-05-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-7b3bd6ba50524d4199ce88db870dc85c2022-12-21T19:11:37ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722018-05-0193276282Obstructive sleep apnea and the severity of coronary artery diseaseAli Vasheghani-Farahani0Fatemeh Kazemnejad1Khosro Sadeghniiat-Haghighi2Soleil Saadat3Parya Tavakoli poor4Tahereh Yazdani5Mohammad Alidoosti6Vahid Ghasem Amooeian7Haleh Ashraf8 Cardiac Primary Prevention Research Center (CPPRC), Tehran Heart Center, Tehran University of Medical Sciences Tehran, Iran Students' Scientific Research Center (SSRC), Cardiac primary prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran Sina trauma research center, Tehran University of Medical Sciences, Tehran, Iran Obesity Research Center, Sina University Hospital, Tehran University of Medical Sciences, Tehran, Iran Obesity Research Center, Sina University Hospital, Tehran University of Medical Sciences, Tehran, Iran Students' Scientific Research Center (SSRC), Cardiac primary prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran Students' Scientific Research Center (SSRC), Cardiac primary prevention Research Center, Tehran University of Medical Sciences, Tehran, Iran Cardiac Primary Prevention Research Center (CPPRC), Tehran Heart Center, Tehran University of Medical Sciences Tehran, Iran Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and severity of atherosclerosis assessed by angiography. Methods: This study included 337 patients undergoing diagnostic coronary angiography at Tehran Heart Center, Iran. The Gensini score was obtained from each patient for coronary angiogram, and OSA were assessed by using Multivariable apnea prediction (MAP) risk index on the day of cardiac catheterization. The Gensini scores increased in accordance with increases in the MAP value. Results: The prevalence rates of three-vessel disease were 68.0% in OSA group and 32.0% in non-OSA group. The MAP index was the most significant independent determinant for the Gensini score. Conclusions: The independent association between OSA and CAD, even after adjustment for traditional confounders, suggests that, OSA should be taken into account when considering risk factors for CAD.http://caspjim.com/browse.php?a_code=A-10-755-2&slc_lang=en&sid=1Atherosclerosis coronary angiography coronary artery disease Gensini score Obstructive sleep apnea |
| spellingShingle | Ali Vasheghani-Farahani Fatemeh Kazemnejad Khosro Sadeghniiat-Haghighi Soleil Saadat Parya Tavakoli poor Tahereh Yazdani Mohammad Alidoosti Vahid Ghasem Amooeian Haleh Ashraf Obstructive sleep apnea and the severity of coronary artery disease Caspian Journal of Internal Medicine Atherosclerosis coronary angiography coronary artery disease Gensini score Obstructive sleep apnea |
| title | Obstructive sleep apnea and the severity of coronary artery disease |
| title_full | Obstructive sleep apnea and the severity of coronary artery disease |
| title_fullStr | Obstructive sleep apnea and the severity of coronary artery disease |
| title_full_unstemmed | Obstructive sleep apnea and the severity of coronary artery disease |
| title_short | Obstructive sleep apnea and the severity of coronary artery disease |
| title_sort | obstructive sleep apnea and the severity of coronary artery disease |
| topic | Atherosclerosis coronary angiography coronary artery disease Gensini score Obstructive sleep apnea |
| url | http://caspjim.com/browse.php?a_code=A-10-755-2&slc_lang=en&sid=1 |
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