Identifying pleiotropic variants and candidate genes for fertility and reproduction traits in Holstein cattle via association studies based on imputed whole-genome sequence genotypes

Identifying pleiotropic variants and candidate genes for fertility and reproduction traits in Holstein cattle via association studies based on imputed whole-genome sequence genotypes

Abstract Background Genetic progress for fertility and reproduction traits in dairy cattle has been limited due to the low heritability of most indicator traits. Moreover, most of the quantitative trait loci (QTL) and candidate genes associated with these traits remain unknown. In this study, we use...

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Bibliographic Details
Main Authors: Shi-Yi Chen, Flavio S. Schenkel, Ana L. P. Melo, Hinayah R. Oliveira, Victor B. Pedrosa, Andre C. Araujo, Melkaye G. Melka, Luiz F. Brito
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Genomics
Subjects:
Cattle breeding
Genome-wide association study
GWAS
QTL
Whole-genome sequence variants
Online Access:https://doi.org/10.1186/s12864-022-08555-z

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