Naloxone induced pulmonary edema
Naloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequen...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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Greater Baltimore Medical Center
2021-01-01
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Series: | Journal of Community Hospital Internal Medicine Perspectives |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/20009666.2020.1854417 |
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author | Sherif Elkattawy Ramez Alyacoub Chidinma Ejikeme Muhammad Atif Masood Noori Carlos Remolina |
author_facet | Sherif Elkattawy Ramez Alyacoub Chidinma Ejikeme Muhammad Atif Masood Noori Carlos Remolina |
author_sort | Sherif Elkattawy |
collection | DOAJ |
description | Naloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequently leading to pulmonary edema. It appears to be more common when higher doses of naloxone are used. We present a case of a patient with opioid overdose came with altered mental status developed early features of pulmonary edema following the administration of multiple doses of naloxone. She responded well with the administration of diuretics and oxygen supplementation. Her oxygen requirements improved and didn’t require mechanical ventilation. |
first_indexed | 2024-04-11T03:44:19Z |
format | Article |
id | doaj.art-7b47f96c2d234cf998450fd014873c03 |
institution | Directory Open Access Journal |
issn | 2000-9666 |
language | English |
last_indexed | 2024-04-11T03:44:19Z |
publishDate | 2021-01-01 |
publisher | Greater Baltimore Medical Center |
record_format | Article |
series | Journal of Community Hospital Internal Medicine Perspectives |
spelling | doaj.art-7b47f96c2d234cf998450fd014873c032023-01-02T03:03:16ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-01-0111113914210.1080/20009666.2020.18544171854417Naloxone induced pulmonary edemaSherif Elkattawy0Ramez Alyacoub1Chidinma Ejikeme2Muhammad Atif Masood Noori3Carlos Remolina4Rutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramRutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramRutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramRutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramTrinitas Regional Medical CenterNaloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequently leading to pulmonary edema. It appears to be more common when higher doses of naloxone are used. We present a case of a patient with opioid overdose came with altered mental status developed early features of pulmonary edema following the administration of multiple doses of naloxone. She responded well with the administration of diuretics and oxygen supplementation. Her oxygen requirements improved and didn’t require mechanical ventilation.http://dx.doi.org/10.1080/20009666.2020.1854417naloxonepulmonary edemaopioids |
spellingShingle | Sherif Elkattawy Ramez Alyacoub Chidinma Ejikeme Muhammad Atif Masood Noori Carlos Remolina Naloxone induced pulmonary edema Journal of Community Hospital Internal Medicine Perspectives naloxone pulmonary edema opioids |
title | Naloxone induced pulmonary edema |
title_full | Naloxone induced pulmonary edema |
title_fullStr | Naloxone induced pulmonary edema |
title_full_unstemmed | Naloxone induced pulmonary edema |
title_short | Naloxone induced pulmonary edema |
title_sort | naloxone induced pulmonary edema |
topic | naloxone pulmonary edema opioids |
url | http://dx.doi.org/10.1080/20009666.2020.1854417 |
work_keys_str_mv | AT sherifelkattawy naloxoneinducedpulmonaryedema AT ramezalyacoub naloxoneinducedpulmonaryedema AT chidinmaejikeme naloxoneinducedpulmonaryedema AT muhammadatifmasoodnoori naloxoneinducedpulmonaryedema AT carlosremolina naloxoneinducedpulmonaryedema |