Naloxone induced pulmonary edema

Naloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequen...

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Main Authors: Sherif Elkattawy, Ramez Alyacoub, Chidinma Ejikeme, Muhammad Atif Masood Noori, Carlos Remolina
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2021-01-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://dx.doi.org/10.1080/20009666.2020.1854417
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author Sherif Elkattawy
Ramez Alyacoub
Chidinma Ejikeme
Muhammad Atif Masood Noori
Carlos Remolina
author_facet Sherif Elkattawy
Ramez Alyacoub
Chidinma Ejikeme
Muhammad Atif Masood Noori
Carlos Remolina
author_sort Sherif Elkattawy
collection DOAJ
description Naloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequently leading to pulmonary edema. It appears to be more common when higher doses of naloxone are used. We present a case of a patient with opioid overdose came with altered mental status developed early features of pulmonary edema following the administration of multiple doses of naloxone. She responded well with the administration of diuretics and oxygen supplementation. Her oxygen requirements improved and didn’t require mechanical ventilation.
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spelling doaj.art-7b47f96c2d234cf998450fd014873c032023-01-02T03:03:16ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-01-0111113914210.1080/20009666.2020.18544171854417Naloxone induced pulmonary edemaSherif Elkattawy0Ramez Alyacoub1Chidinma Ejikeme2Muhammad Atif Masood Noori3Carlos Remolina4Rutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramRutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramRutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramRutgers New Jersey Medical School/Trinitas Regional Medical Center ProgramTrinitas Regional Medical CenterNaloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequently leading to pulmonary edema. It appears to be more common when higher doses of naloxone are used. We present a case of a patient with opioid overdose came with altered mental status developed early features of pulmonary edema following the administration of multiple doses of naloxone. She responded well with the administration of diuretics and oxygen supplementation. Her oxygen requirements improved and didn’t require mechanical ventilation.http://dx.doi.org/10.1080/20009666.2020.1854417naloxonepulmonary edemaopioids
spellingShingle Sherif Elkattawy
Ramez Alyacoub
Chidinma Ejikeme
Muhammad Atif Masood Noori
Carlos Remolina
Naloxone induced pulmonary edema
Journal of Community Hospital Internal Medicine Perspectives
naloxone
pulmonary edema
opioids
title Naloxone induced pulmonary edema
title_full Naloxone induced pulmonary edema
title_fullStr Naloxone induced pulmonary edema
title_full_unstemmed Naloxone induced pulmonary edema
title_short Naloxone induced pulmonary edema
title_sort naloxone induced pulmonary edema
topic naloxone
pulmonary edema
opioids
url http://dx.doi.org/10.1080/20009666.2020.1854417
work_keys_str_mv AT sherifelkattawy naloxoneinducedpulmonaryedema
AT ramezalyacoub naloxoneinducedpulmonaryedema
AT chidinmaejikeme naloxoneinducedpulmonaryedema
AT muhammadatifmasoodnoori naloxoneinducedpulmonaryedema
AT carlosremolina naloxoneinducedpulmonaryedema