A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting—high coverage and safety, but no significant impact on transmission

A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting—high coverage and safety, but no significant impact on transmission

Abstract Background Mass drug administration (MDA) has the potential to interrupt malaria transmission and has been suggested as a tool for malaria elimination in low-endemic settings. This study aimed to determine the effectiveness and safety of two rounds of MDA in Zanzibar, a pre-elimination sett...

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Bibliographic Details
Main Authors: Ulrika Morris, Mwinyi I. Msellem, Humphrey Mkali, Atiqul Islam, Berit Aydin-Schmidt, Irina Jovel, Shija Joseph Shija, Mwinyi Khamis, Safia Mohammed Ali, Lamija Hodzic, Ellinor Magnusson, Eugenie Poirot, Adam Bennett, Michael C. Sachs, Joel Tarning, Andreas Mårtensson, Abdullah S. Ali, Anders Björkman
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medicine
Subjects:
Mass drug administration
Malaria
Elimination
Low transmission
Dihydroartemisinin-piperaquine
Single low-dose primaquine
Online Access:http://link.springer.com/article/10.1186/s12916-018-1202-8

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