STAT3 Inhibition in a Murine Model of Human Breast Cancer-Induced Bone Pain Delays Onset of Nociception

STAT3 Inhibition in a Murine Model of Human Breast Cancer-Induced Bone Pain Delays Onset of Nociception

Introduction/Aim: Alterations in extracellular glutamate levels have been previously found to contribute to cancer-induced bone pain (CIBP). Increased activity of system xc-, a cystine-glutamate membrane antiporter, has been previously implicated in our lab in these nociceptive behaviours. System xc...

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Bibliographic Details
Main Authors: Manu Sharma, Katja Linher-Melville, Jesse Sidhu, Peter Nakhla, Gurmit Singh
Format: Article
Language:English
Published: Taylor & Francis Group 2019-07-01
Series:Canadian Journal of Pain
Subjects:
STAT3
cancer-induced bone pain
nociceptive
allodynia
breast cancer
cancer
cancer pain
Online Access:http://dx.doi.org/10.1080/24740527.2019.1641060

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