Liquid Biopsy in Thyroid Cancer: New Insight
Thyroid cancer, one of the most widespread malignancies of the endocrine-related system that over the past three decades, has a vivid increasing rate. The diagnosis and management of it is dependent on the tumor type and stage. Thyroid cancer is divided into four main types, including PTC (papillary...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2018-07-01
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| Series: | International Journal of Hematology-Oncology and Stem Cell Research |
| Subjects: | |
| Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/926 |
| _version_ | 1827835763551633408 |
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| author | Fatemeh Khatami Seyed Mohammad Tavangar |
| author_facet | Fatemeh Khatami Seyed Mohammad Tavangar |
| author_sort | Fatemeh Khatami |
| collection | DOAJ |
| description | Thyroid cancer, one of the most widespread malignancies of the endocrine-related system that over the past three decades, has a vivid increasing rate. The diagnosis and management of it is dependent on the tumor type and stage. Thyroid cancer is divided into four main types, including PTC (papillary thyroid carcinoma), FTC (follicular thyroid carcinoma), MTC (medullarly thyroid carcinoma), and ATC (anaplastic thyroid carcinoma). The development of the noninvasive diagnostic tool for plasma genotyping, also known as “liquid biopsy”, brings a new insight for cancer diagnosis and prognosis. It is mainly containing circulating tumor DNA (ctDNA), circulating tumor cell (CTC), exosomes and extrachromosomal circular DNA (ecDNA). Liquid biopsy as a new plasma genotyping source brings a new prospective of tumor monitoring and therapy. It beneficially reduces the need of tissue biopsy and made early recognition of relapse as well. This article summarizes its components characteristics and their benefit in diagnosis and treatment of thyroid cancer. |
| first_indexed | 2024-03-12T06:14:48Z |
| format | Article |
| id | doaj.art-7b4ef9fca1244522b940937a5643536a |
| institution | Directory Open Access Journal |
| issn | 2008-2207 |
| language | English |
| last_indexed | 2024-03-12T06:14:48Z |
| publishDate | 2018-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | International Journal of Hematology-Oncology and Stem Cell Research |
| spelling | doaj.art-7b4ef9fca1244522b940937a5643536a2023-09-03T02:42:25ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072018-07-01123Liquid Biopsy in Thyroid Cancer: New InsightFatemeh Khatami0Seyed Mohammad Tavangar1Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranThyroid cancer, one of the most widespread malignancies of the endocrine-related system that over the past three decades, has a vivid increasing rate. The diagnosis and management of it is dependent on the tumor type and stage. Thyroid cancer is divided into four main types, including PTC (papillary thyroid carcinoma), FTC (follicular thyroid carcinoma), MTC (medullarly thyroid carcinoma), and ATC (anaplastic thyroid carcinoma). The development of the noninvasive diagnostic tool for plasma genotyping, also known as “liquid biopsy”, brings a new insight for cancer diagnosis and prognosis. It is mainly containing circulating tumor DNA (ctDNA), circulating tumor cell (CTC), exosomes and extrachromosomal circular DNA (ecDNA). Liquid biopsy as a new plasma genotyping source brings a new prospective of tumor monitoring and therapy. It beneficially reduces the need of tissue biopsy and made early recognition of relapse as well. This article summarizes its components characteristics and their benefit in diagnosis and treatment of thyroid cancer.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/926BiopsyCarcinomaThyroid CancerEndocrine System DiseasescfDNACTCs |
| spellingShingle | Fatemeh Khatami Seyed Mohammad Tavangar Liquid Biopsy in Thyroid Cancer: New Insight International Journal of Hematology-Oncology and Stem Cell Research Biopsy Carcinoma Thyroid Cancer Endocrine System Diseases cfDNA CTCs |
| title | Liquid Biopsy in Thyroid Cancer: New Insight |
| title_full | Liquid Biopsy in Thyroid Cancer: New Insight |
| title_fullStr | Liquid Biopsy in Thyroid Cancer: New Insight |
| title_full_unstemmed | Liquid Biopsy in Thyroid Cancer: New Insight |
| title_short | Liquid Biopsy in Thyroid Cancer: New Insight |
| title_sort | liquid biopsy in thyroid cancer new insight |
| topic | Biopsy Carcinoma Thyroid Cancer Endocrine System Diseases cfDNA CTCs |
| url | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/926 |
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