Probable Secondary Infections in Households of SARS Patients in Hong Kong

Although severe acute respiratory syndrome (SARS) is highly infectious in clinical settings, SARS has not been well examined in household settings. The household and household member attack rates were calculated for 1,214 SARS case-patients and their household members, stratified by two phases of th...

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Main Authors: Joseph T.F. Lau, Mason Lau, Jean H. Kim, Eric Wong, Hi-Yi Tsui, Thomas Tsang, Tze Wai Wong
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2004-02-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/10/2/03-0626_article
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author Joseph T.F. Lau
Mason Lau
Jean H. Kim
Eric Wong
Hi-Yi Tsui
Thomas Tsang
Tze Wai Wong
author_facet Joseph T.F. Lau
Mason Lau
Jean H. Kim
Eric Wong
Hi-Yi Tsui
Thomas Tsang
Tze Wai Wong
author_sort Joseph T.F. Lau
collection DOAJ
description Although severe acute respiratory syndrome (SARS) is highly infectious in clinical settings, SARS has not been well examined in household settings. The household and household member attack rates were calculated for 1,214 SARS case-patients and their household members, stratified by two phases of the epidemic. A case-control analysis identified risk factors for secondary infection. Secondary infection occurred in 14.9% (22.1% versus 11% in earlier and later phases) of all households and 8% (11.7% versus 5.9% in the earlier and later phases) of all household members. Healthcare workers’ households were less likely to be affected. Risk factors from the multivariate analysis included at-home duration before hospitalization, hospital visitation to the SARS patient (and mask use during the visit), and frequency of close contact. SARS transmission at the household level was not negligible in Hong Kong. Transmission rates may be greatly reduced with precautionary measures taken by household members of SARS patients.
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spelling doaj.art-7b4f0089440d4a849f87c7246dcf80612022-12-22T00:50:19ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592004-02-0110223624310.3201/eid1002.030626Probable Secondary Infections in Households of SARS Patients in Hong KongJoseph T.F. LauMason LauJean H. KimEric WongHi-Yi TsuiThomas TsangTze Wai WongAlthough severe acute respiratory syndrome (SARS) is highly infectious in clinical settings, SARS has not been well examined in household settings. The household and household member attack rates were calculated for 1,214 SARS case-patients and their household members, stratified by two phases of the epidemic. A case-control analysis identified risk factors for secondary infection. Secondary infection occurred in 14.9% (22.1% versus 11% in earlier and later phases) of all households and 8% (11.7% versus 5.9% in the earlier and later phases) of all household members. Healthcare workers’ households were less likely to be affected. Risk factors from the multivariate analysis included at-home duration before hospitalization, hospital visitation to the SARS patient (and mask use during the visit), and frequency of close contact. SARS transmission at the household level was not negligible in Hong Kong. Transmission rates may be greatly reduced with precautionary measures taken by household members of SARS patients.https://wwwnc.cdc.gov/eid/article/10/2/03-0626_articleSARSsecondary infectionsepidemiologyHong Kong
spellingShingle Joseph T.F. Lau
Mason Lau
Jean H. Kim
Eric Wong
Hi-Yi Tsui
Thomas Tsang
Tze Wai Wong
Probable Secondary Infections in Households of SARS Patients in Hong Kong
Emerging Infectious Diseases
SARS
secondary infections
epidemiology
Hong Kong
title Probable Secondary Infections in Households of SARS Patients in Hong Kong
title_full Probable Secondary Infections in Households of SARS Patients in Hong Kong
title_fullStr Probable Secondary Infections in Households of SARS Patients in Hong Kong
title_full_unstemmed Probable Secondary Infections in Households of SARS Patients in Hong Kong
title_short Probable Secondary Infections in Households of SARS Patients in Hong Kong
title_sort probable secondary infections in households of sars patients in hong kong
topic SARS
secondary infections
epidemiology
Hong Kong
url https://wwwnc.cdc.gov/eid/article/10/2/03-0626_article
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