A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes
The study aims to address the need for accurate and real-time monitoring of glucose levels in college athletes during physical activities. This work reports on the development of an electrochemical sensor that uses glucose oxidase (GOx) immobilized on PdO nanoparticles to reduce graphene oxide (rGO)...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Alexandria Engineering Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110016824002965 |
| _version_ | 1797220605303455744 |
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| author | Li Chen Yong Zhang Tongyi Hu |
| author_facet | Li Chen Yong Zhang Tongyi Hu |
| author_sort | Li Chen |
| collection | DOAJ |
| description | The study aims to address the need for accurate and real-time monitoring of glucose levels in college athletes during physical activities. This work reports on the development of an electrochemical sensor that uses glucose oxidase (GOx) immobilized on PdO nanoparticles to reduce graphene oxide (rGO) nanocomposite printed on a cellulose substrate (GOx/PdO-rGO/C-PE). The successful reduction of GO to rGO, the production of the PdO-rGO nanocomposite, and the electropolymerization of GOx on the PdO-rGO nanocomposite were all validated by the material characterization. The biosensor's electrochemical response investigation showed that its detection limit was 0.046 μM and its sensitivity was 0.03239 μA/μM. Excellent stability, reproducibility, and glucose selectivity were shown by the GOx/PdO-rGO/C-PE, which makes it a viable option for consistent and dependable glucose sensing in real-world applications. The real sample analysis assessed how well the combination of GOx/PdO-rGO/C-PE could identify glucose in human serum. Furthermore, under a variety of real-world conditions, such as during various physical activities and at different times of the day, the sensor demonstrated outstanding performance in real-time glucose monitoring. These findings imply that the GOx/PdO-rGO/C-PE offers accurate and dependable readings in the field of non-invasive glucose monitoring, which will be especially helpful for college and professional athletes. |
| first_indexed | 2024-04-24T12:52:12Z |
| format | Article |
| id | doaj.art-7b4fcfd3cbb14944af01a781432778a4 |
| institution | Directory Open Access Journal |
| issn | 1110-0168 |
| language | English |
| last_indexed | 2024-04-24T12:52:12Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Alexandria Engineering Journal |
| spelling | doaj.art-7b4fcfd3cbb14944af01a781432778a42024-04-06T04:39:31ZengElsevierAlexandria Engineering Journal1110-01682024-05-0195321332A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletesLi Chen0Yong Zhang1Tongyi Hu2College of Physical Education and Health Science, Chongqing Normal University, Gaoxinqu, Chongqing 401331, ChinaSichuan International Studies University, Shapingba, Chongqing 400031, China; Corresponding author.Foundation Department, Chongqing Medical and Pharmaceutical College, Gaoxinqu, Chongqing 401331, ChinaThe study aims to address the need for accurate and real-time monitoring of glucose levels in college athletes during physical activities. This work reports on the development of an electrochemical sensor that uses glucose oxidase (GOx) immobilized on PdO nanoparticles to reduce graphene oxide (rGO) nanocomposite printed on a cellulose substrate (GOx/PdO-rGO/C-PE). The successful reduction of GO to rGO, the production of the PdO-rGO nanocomposite, and the electropolymerization of GOx on the PdO-rGO nanocomposite were all validated by the material characterization. The biosensor's electrochemical response investigation showed that its detection limit was 0.046 μM and its sensitivity was 0.03239 μA/μM. Excellent stability, reproducibility, and glucose selectivity were shown by the GOx/PdO-rGO/C-PE, which makes it a viable option for consistent and dependable glucose sensing in real-world applications. The real sample analysis assessed how well the combination of GOx/PdO-rGO/C-PE could identify glucose in human serum. Furthermore, under a variety of real-world conditions, such as during various physical activities and at different times of the day, the sensor demonstrated outstanding performance in real-time glucose monitoring. These findings imply that the GOx/PdO-rGO/C-PE offers accurate and dependable readings in the field of non-invasive glucose monitoring, which will be especially helpful for college and professional athletes.http://www.sciencedirect.com/science/article/pii/S1110016824002965PdO nanoparticlesReduced Graphene OxideGlucose monitoringAthletesDifferential Pulse Voltammetry |
| spellingShingle | Li Chen Yong Zhang Tongyi Hu A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes Alexandria Engineering Journal PdO nanoparticles Reduced Graphene Oxide Glucose monitoring Athletes Differential Pulse Voltammetry |
| title | A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes |
| title_full | A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes |
| title_fullStr | A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes |
| title_full_unstemmed | A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes |
| title_short | A graphene oxide-modified biosensor for non-invasive glucose monitoring in college athletes |
| title_sort | graphene oxide modified biosensor for non invasive glucose monitoring in college athletes |
| topic | PdO nanoparticles Reduced Graphene Oxide Glucose monitoring Athletes Differential Pulse Voltammetry |
| url | http://www.sciencedirect.com/science/article/pii/S1110016824002965 |
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