Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study

BackgroundWeb-based resources and social media platforms play an increasingly important role in health-related knowledge and experience sharing. There is a growing interest in the use of these novel data sources for epidemiological surveillance of substance use behaviors and...

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Main Authors: Usha Lokala, Francois Lamy, Raminta Daniulaityte, Manas Gaur, Amelie Gyrard, Krishnaprasad Thirunarayan, Ugur Kursuncu, Amit Sheth
Format: Article
Language:English
Published: JMIR Publications 2022-12-01
Series:JMIR Public Health and Surveillance
Online Access:https://publichealth.jmir.org/2022/12/e24938
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author Usha Lokala
Francois Lamy
Raminta Daniulaityte
Manas Gaur
Amelie Gyrard
Krishnaprasad Thirunarayan
Ugur Kursuncu
Amit Sheth
author_facet Usha Lokala
Francois Lamy
Raminta Daniulaityte
Manas Gaur
Amelie Gyrard
Krishnaprasad Thirunarayan
Ugur Kursuncu
Amit Sheth
author_sort Usha Lokala
collection DOAJ
description BackgroundWeb-based resources and social media platforms play an increasingly important role in health-related knowledge and experience sharing. There is a growing interest in the use of these novel data sources for epidemiological surveillance of substance use behaviors and trends. ObjectiveThe key aims were to describe the development and application of the drug abuse ontology (DAO) as a framework for analyzing web-based and social media data to inform public health and substance use research in the following areas: determining user knowledge, attitudes, and behaviors related to nonmedical use of buprenorphine and illicitly manufactured opioids through the analysis of web forum data Prescription Drug Abuse Online Surveillance; analyzing patterns and trends of cannabis product use in the context of evolving cannabis legalization policies in the United States through analysis of Twitter and web forum data (eDrugTrends); assessing trends in the availability of novel synthetic opioids through the analysis of cryptomarket data (eDarkTrends); and analyzing COVID-19 pandemic trends in social media data related to 13 states in the United States as per Mental Health America reports. MethodsThe domain and scope of the DAO were defined using competency questions from popular ontology methodology (101 ontology development). The 101 method includes determining the domain and scope of ontology, reusing existing knowledge, enumerating important terms in ontology, defining the classes, their properties and creating instances of the classes. The quality of the ontology was evaluated using a set of tools and best practices recognized by the semantic web community and the artificial intelligence community that engage in natural language processing. ResultsThe current version of the DAO comprises 315 classes, 31 relationships, and 814 instances among the classes. The ontology is flexible and can easily accommodate new concepts. The integration of the ontology with machine learning algorithms dramatically decreased the false alarm rate by adding external knowledge to the machine learning process. The ontology is recurrently updated to capture evolving concepts in different contexts and applied to analyze data related to social media and dark web marketplaces. ConclusionsThe DAO provides a powerful framework and a useful resource that can be expanded and adapted to a wide range of substance use and mental health domains to help advance big data analytics of web-based data for substance use epidemiology research.
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spelling doaj.art-7b520ec8d8854ae4bf4925736d7e924b2023-08-28T23:29:29ZengJMIR PublicationsJMIR Public Health and Surveillance2369-29602022-12-01812e2493810.2196/24938Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development StudyUsha Lokalahttps://orcid.org/0000-0001-6186-2171Francois Lamyhttps://orcid.org/0000-0001-6542-1381Raminta Daniulaitytehttps://orcid.org/0000-0001-6507-3866Manas Gaurhttps://orcid.org/0000-0002-5411-2230Amelie Gyrardhttps://orcid.org/0000-0003-3938-5617Krishnaprasad Thirunarayanhttps://orcid.org/0000-0002-7041-6963Ugur Kursuncuhttps://orcid.org/0000-0002-8108-9590Amit Shethhttps://orcid.org/0000-0002-0021-5293 BackgroundWeb-based resources and social media platforms play an increasingly important role in health-related knowledge and experience sharing. There is a growing interest in the use of these novel data sources for epidemiological surveillance of substance use behaviors and trends. ObjectiveThe key aims were to describe the development and application of the drug abuse ontology (DAO) as a framework for analyzing web-based and social media data to inform public health and substance use research in the following areas: determining user knowledge, attitudes, and behaviors related to nonmedical use of buprenorphine and illicitly manufactured opioids through the analysis of web forum data Prescription Drug Abuse Online Surveillance; analyzing patterns and trends of cannabis product use in the context of evolving cannabis legalization policies in the United States through analysis of Twitter and web forum data (eDrugTrends); assessing trends in the availability of novel synthetic opioids through the analysis of cryptomarket data (eDarkTrends); and analyzing COVID-19 pandemic trends in social media data related to 13 states in the United States as per Mental Health America reports. MethodsThe domain and scope of the DAO were defined using competency questions from popular ontology methodology (101 ontology development). The 101 method includes determining the domain and scope of ontology, reusing existing knowledge, enumerating important terms in ontology, defining the classes, their properties and creating instances of the classes. The quality of the ontology was evaluated using a set of tools and best practices recognized by the semantic web community and the artificial intelligence community that engage in natural language processing. ResultsThe current version of the DAO comprises 315 classes, 31 relationships, and 814 instances among the classes. The ontology is flexible and can easily accommodate new concepts. The integration of the ontology with machine learning algorithms dramatically decreased the false alarm rate by adding external knowledge to the machine learning process. The ontology is recurrently updated to capture evolving concepts in different contexts and applied to analyze data related to social media and dark web marketplaces. ConclusionsThe DAO provides a powerful framework and a useful resource that can be expanded and adapted to a wide range of substance use and mental health domains to help advance big data analytics of web-based data for substance use epidemiology research.https://publichealth.jmir.org/2022/12/e24938
spellingShingle Usha Lokala
Francois Lamy
Raminta Daniulaityte
Manas Gaur
Amelie Gyrard
Krishnaprasad Thirunarayan
Ugur Kursuncu
Amit Sheth
Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study
JMIR Public Health and Surveillance
title Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study
title_full Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study
title_fullStr Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study
title_full_unstemmed Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study
title_short Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study
title_sort drug abuse ontology to harness web based data for substance use epidemiology research ontology development study
url https://publichealth.jmir.org/2022/12/e24938
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