Promotion of intestinal peristalsis by Bifidobacterium spp. capable of hydrolysing sennosides in mice.

BACKGROUND:While there are a variety of identifiable causes of constipation, even idiopathic constipation has different possible mechanisms. Sennosides, the main laxative constituents of Daio, an ancient Kampo medicine, are prodrugs that are converted to an active principle, rheinanthrone, by intest...

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Bibliographic Details
Main Authors: Mitsuharu Matsumoto, Atsushi Ishige, Yuka Yazawa, Manami Kondo, Koji Muramatsu, Kenji Watanabe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3284505?pdf=render