Dosage Compensation of the X Chromosome during Sheep Testis Development Revealed by Single-Cell RNA Sequencing

Dosage Compensation of the X Chromosome during Sheep Testis Development Revealed by Single-Cell RNA Sequencing

Dosage compensation is a mechanism first proposed by Susumu Ohno, whereby X inactivation balances X gene output between males (XY) and females (XX), while X upregulation balances X genes with autosomal gene output. These mechanisms have been actively studied in Drosophila and mice, but research rega...

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Bibliographic Details
Main Authors: Jie Su, Yue Zhang, Hong Su, Caiyun Wang, Daqing Wang, Yanyan Yang, Xiunan Li, Wangmei Qi, Haijun Li, Xihe Li, Yongli Song, Guifang Cao
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Animals
Subjects:
dosage compensation
single-cell RNA sequencing
sheep testis
Online Access:https://www.mdpi.com/2076-2615/12/17/2169

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