Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish

Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish

Insulin-like growth factor 1 (IGF1) is an essential effector of the growth hormone (GH)/IGF1 axis for somatic growth regulation in mammals. However, its functions have not been thoroughly investigated in zebrafish in vivo. In this study, the igf1-deficient zebrafish model was developed using the CRI...

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Bibliographic Details
Main Authors: Ningmei Zeng, Jiankang Bao, TingTing Shu, Chuang Shi, Gang Zhai, Xia Jin, Jiangyan He, Qiyong Lou, Zhan Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
sexual dimorphism
hepatic metabolism
glucose uptake
lactate/pyruvate ratio
igf1
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.879962/full

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