Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan

<p>Abstract</p> <p>Background</p> <p>Peripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients with end-stage renal di...

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Main Authors: Lee Chun-Chuan, Wu Chih-Jen, Chou Li-Hua, Shen Su-Mei, Chiang Sheng-Fang, Jen Pi-Chu, Yeh Mei-Ching, Pan Chi-Feng
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Nephrology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2369/13/100
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author Lee Chun-Chuan
Wu Chih-Jen
Chou Li-Hua
Shen Su-Mei
Chiang Sheng-Fang
Jen Pi-Chu
Yeh Mei-Ching
Pan Chi-Feng
author_facet Lee Chun-Chuan
Wu Chih-Jen
Chou Li-Hua
Shen Su-Mei
Chiang Sheng-Fang
Jen Pi-Chu
Yeh Mei-Ching
Pan Chi-Feng
author_sort Lee Chun-Chuan
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Peripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients with end-stage renal disease (ESRD), especially those on hemodialysis (HD).</p> <p>Methods</p> <p>The records of 484 patients with end-stage renal disease who were on HD or peritoneal dialysis (PD) were reviewed. PAD was diagnosed based on the ankle-brachial pressure index (ABI). Demographic and clinical characteristics were analyzed.</p> <p>Results</p> <p>PAD had an overall prevalence of 18.2% and was significantly more common in HD patients (21.8%) than in PD patients (4.8%). Advanced age, diabetes mellitus, smoking, low parathyroid hormone level, elevated serum ferritin, elevated serum glucose, and low serum creatinine levels increased the risk for PAD. PAD was independently associated with advanced age, diabetes mellitus, duration of dialysis, low serum creatinine, and hyperlipidemia. PD patients had a significantly lower prevalence of PAD than HD patients, maybe due to their younger age and lower prevalence of diabetes mellitus in this present study.</p> <p>Conclusions</p> <p>The prevalence of PAD was greater in the HD group than the PD group. Most of the risk factors for PAD were specific to HD, and no analyzed factor was significantly associated with PAD in PD patients.</p>
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spelling doaj.art-7b58f4b2a2cc47e196431305d5053f882022-12-22T02:50:06ZengBMCBMC Nephrology1471-23692012-09-0113110010.1186/1471-2369-13-100Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in TaiwanLee Chun-ChuanWu Chih-JenChou Li-HuaShen Su-MeiChiang Sheng-FangJen Pi-ChuYeh Mei-ChingPan Chi-Feng<p>Abstract</p> <p>Background</p> <p>Peripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients with end-stage renal disease (ESRD), especially those on hemodialysis (HD).</p> <p>Methods</p> <p>The records of 484 patients with end-stage renal disease who were on HD or peritoneal dialysis (PD) were reviewed. PAD was diagnosed based on the ankle-brachial pressure index (ABI). Demographic and clinical characteristics were analyzed.</p> <p>Results</p> <p>PAD had an overall prevalence of 18.2% and was significantly more common in HD patients (21.8%) than in PD patients (4.8%). Advanced age, diabetes mellitus, smoking, low parathyroid hormone level, elevated serum ferritin, elevated serum glucose, and low serum creatinine levels increased the risk for PAD. PAD was independently associated with advanced age, diabetes mellitus, duration of dialysis, low serum creatinine, and hyperlipidemia. PD patients had a significantly lower prevalence of PAD than HD patients, maybe due to their younger age and lower prevalence of diabetes mellitus in this present study.</p> <p>Conclusions</p> <p>The prevalence of PAD was greater in the HD group than the PD group. Most of the risk factors for PAD were specific to HD, and no analyzed factor was significantly associated with PAD in PD patients.</p>http://www.biomedcentral.com/1471-2369/13/100Ankle-brachial pressure index (ABI)Cardiovascular diseaseEnd-stage renal diseaseHemodialysisPeritoneal dialysisPeripheral artery disease
spellingShingle Lee Chun-Chuan
Wu Chih-Jen
Chou Li-Hua
Shen Su-Mei
Chiang Sheng-Fang
Jen Pi-Chu
Yeh Mei-Ching
Pan Chi-Feng
Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan
BMC Nephrology
Ankle-brachial pressure index (ABI)
Cardiovascular disease
End-stage renal disease
Hemodialysis
Peritoneal dialysis
Peripheral artery disease
title Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan
title_full Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan
title_fullStr Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan
title_full_unstemmed Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan
title_short Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan
title_sort peripheral artery disease in peritoneal dialysis and hemodialysis patients single center retrospective study in taiwan
topic Ankle-brachial pressure index (ABI)
Cardiovascular disease
End-stage renal disease
Hemodialysis
Peritoneal dialysis
Peripheral artery disease
url http://www.biomedcentral.com/1471-2369/13/100
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