Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers

Chromatography on chiral stationary phases and electrophoresis in the presence of chiral selectors have become essential tools for the determination of enantiomeric purity in connection with synthesis and with biological studies of chiral molecules. Moreover, the chromatographic resolution...

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Main Author: Eric R. Francotte
Format: Article
Language:deu
Published: Swiss Chemical Society 1997-10-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/2879
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author Eric R. Francotte
author_facet Eric R. Francotte
author_sort Eric R. Francotte
collection DOAJ
description Chromatography on chiral stationary phases and electrophoresis in the presence of chiral selectors have become essential tools for the determination of enantiomeric purity in connection with synthesis and with biological studies of chiral molecules. Moreover, the chromatographic resolution of racemates on a preparative scale compels increasing recognition as alternative to 'preparing' pure enantiomers. The state-of-the-art of enantioselective chromatography in the analytical and preparative field is reviewed with particular emphasis on the achievements carried out in Switzerland.
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spelling doaj.art-7b58f98ba4734a02a854cbb6e566a9c02022-12-22T00:01:10ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241997-10-015110Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of EnantiomersEric R. Francotte Chromatography on chiral stationary phases and electrophoresis in the presence of chiral selectors have become essential tools for the determination of enantiomeric purity in connection with synthesis and with biological studies of chiral molecules. Moreover, the chromatographic resolution of racemates on a preparative scale compels increasing recognition as alternative to 'preparing' pure enantiomers. The state-of-the-art of enantioselective chromatography in the analytical and preparative field is reviewed with particular emphasis on the achievements carried out in Switzerland. https://www.chimia.ch/chimia/article/view/2879
spellingShingle Eric R. Francotte
Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
CHIMIA
title Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
title_full Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
title_fullStr Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
title_full_unstemmed Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
title_short Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
title_sort enantioselective chromatography an essential and versatile tool for the analytical and preparative separation of enantiomers
url https://www.chimia.ch/chimia/article/view/2879
work_keys_str_mv AT ericrfrancotte enantioselectivechromatographyanessentialandversatiletoolfortheanalyticalandpreparativeseparationofenantiomers