Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis
Inflammatory fibroid polyp (IFP), initially considered a reactive process, is now recognized as a benign mesenchymal neoplasm of the gastrointestinal tract. We report a case of a 68-year-old woman with medically refractory Crohn disease that presented with intussusception requiring surgical interven...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2023/9417141 |
| _version_ | 1797843384743755776 |
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| author | Asma Khalid Abu-Salah Eric Brocken Hector Mesa Katrina Collins |
| author_facet | Asma Khalid Abu-Salah Eric Brocken Hector Mesa Katrina Collins |
| author_sort | Asma Khalid Abu-Salah |
| collection | DOAJ |
| description | Inflammatory fibroid polyp (IFP), initially considered a reactive process, is now recognized as a benign mesenchymal neoplasm of the gastrointestinal tract. We report a case of a 68-year-old woman with medically refractory Crohn disease that presented with intussusception requiring surgical intervention. The resection revealed a jejunal mass consisting of a submucosal proliferation of bland spindle cells in a fibrous stroma infiltrated by numerous eosinophils. By immunohistochemistry, the lesion was positive for vimentin and negative for desmin, smooth muscle actin (SMA), S-100, CD117, DOG1, ALK (D5F3), Melan-A, HMB-45, CD34, and STAT6. Ki-67 proliferative index was low (<1%). The mass was classified as IFP by its characteristic morphology and associated eosinophilia. IFP should be considered in the differential diagnosis of adults with intussusception or bowel obstruction. Definitive treatment typically requires surgical resection of the involved bowel segment. |
| first_indexed | 2024-04-09T17:04:18Z |
| format | Article |
| id | doaj.art-7b5ac1ec95d24c878da083cc57e36f0d |
| institution | Directory Open Access Journal |
| issn | 2090-679X |
| language | English |
| last_indexed | 2024-04-09T17:04:18Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj.art-7b5ac1ec95d24c878da083cc57e36f0d2023-04-21T00:00:13ZengHindawi LimitedCase Reports in Pathology2090-679X2023-01-01202310.1155/2023/9417141Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential DiagnosisAsma Khalid Abu-Salah0Eric Brocken1Hector Mesa2Katrina Collins3Department of PathologyDepartment of PathologyDepartment of PathologyDepartment of PathologyInflammatory fibroid polyp (IFP), initially considered a reactive process, is now recognized as a benign mesenchymal neoplasm of the gastrointestinal tract. We report a case of a 68-year-old woman with medically refractory Crohn disease that presented with intussusception requiring surgical intervention. The resection revealed a jejunal mass consisting of a submucosal proliferation of bland spindle cells in a fibrous stroma infiltrated by numerous eosinophils. By immunohistochemistry, the lesion was positive for vimentin and negative for desmin, smooth muscle actin (SMA), S-100, CD117, DOG1, ALK (D5F3), Melan-A, HMB-45, CD34, and STAT6. Ki-67 proliferative index was low (<1%). The mass was classified as IFP by its characteristic morphology and associated eosinophilia. IFP should be considered in the differential diagnosis of adults with intussusception or bowel obstruction. Definitive treatment typically requires surgical resection of the involved bowel segment.http://dx.doi.org/10.1155/2023/9417141 |
| spellingShingle | Asma Khalid Abu-Salah Eric Brocken Hector Mesa Katrina Collins Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis Case Reports in Pathology |
| title | Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis |
| title_full | Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis |
| title_fullStr | Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis |
| title_full_unstemmed | Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis |
| title_short | Jejunal Intussusception Secondary to a Large Inflammatory Fibroid Polyp: A Case Report and Discussion of Differential Diagnosis |
| title_sort | jejunal intussusception secondary to a large inflammatory fibroid polyp a case report and discussion of differential diagnosis |
| url | http://dx.doi.org/10.1155/2023/9417141 |
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