Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair
Recent studies demonstrate that patients with a shrinking abdominal aortic aneurysm (AAA), one-year after endovascular repair (EVAR), have better long-term outcomes than patients with a stable AAA. It is not known what factors determine whether an AAA will shrink or not. In this study, a range of pa...
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| Format: | Article |
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MDPI AG
2022-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/5/1394 |
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| author | Rianne E. van Rijswijk Erik Groot Jebbink Suzanne Holewijn Nicky Stoop Steven M. van Sterkenburg Michel M. P. J. Reijnen |
| author_facet | Rianne E. van Rijswijk Erik Groot Jebbink Suzanne Holewijn Nicky Stoop Steven M. van Sterkenburg Michel M. P. J. Reijnen |
| author_sort | Rianne E. van Rijswijk |
| collection | DOAJ |
| description | Recent studies demonstrate that patients with a shrinking abdominal aortic aneurysm (AAA), one-year after endovascular repair (EVAR), have better long-term outcomes than patients with a stable AAA. It is not known what factors determine whether an AAA will shrink or not. In this study, a range of parameters was investigated to identify their use in differentiating patients that will develop a shrinking AAA from those with a stable AAA one-year after EVAR. Hundred-seventy-four patients (67 shrinking AAA, 107 stable AAA) who underwent elective, infrarenal EVAR were enrolled between 2011–2018. Long-term survival was significantly better in patients with a shrinking AAA, compared to those with a stable AAA (<i>p</i> = 0.038). Larger preoperative maximum AAA diameter was associated with an increased likelihood of developing AAA shrinkage one-year after EVAR—whereas older age and larger preoperative infrarenal β angle were associated with a reduced likelihood of AAA shrinkage. However, this multivariate logistic regression model was only able to correctly identify 66.7% of patients with AAA shrinkage from the total cohort. This is not sufficient for implementation in clinical care, and therefore future research is recommended to dive deeper into AAA anatomy, and explore potential predictors using artificial intelligence and radiomics. |
| first_indexed | 2024-03-09T20:34:06Z |
| format | Article |
| id | doaj.art-7b5b9b0bc0c74659adbcea452f3ee9f7 |
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| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T20:34:06Z |
| publishDate | 2022-03-01 |
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| record_format | Article |
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| spelling | doaj.art-7b5b9b0bc0c74659adbcea452f3ee9f72023-11-23T23:15:14ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01115139410.3390/jcm11051394Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular RepairRianne E. van Rijswijk0Erik Groot Jebbink1Suzanne Holewijn2Nicky Stoop3Steven M. van Sterkenburg4Michel M. P. J. Reijnen5Department of Vascular Surgery, Rijnstate, 6815 AD Arnhem, The NetherlandsDepartment of Vascular Surgery, Rijnstate, 6815 AD Arnhem, The NetherlandsDepartment of Vascular Surgery, Rijnstate, 6815 AD Arnhem, The NetherlandsDepartment of Vascular Surgery, Rijnstate, 6815 AD Arnhem, The NetherlandsDepartment of Vascular Surgery, Rijnstate, 6815 AD Arnhem, The NetherlandsDepartment of Vascular Surgery, Rijnstate, 6815 AD Arnhem, The NetherlandsRecent studies demonstrate that patients with a shrinking abdominal aortic aneurysm (AAA), one-year after endovascular repair (EVAR), have better long-term outcomes than patients with a stable AAA. It is not known what factors determine whether an AAA will shrink or not. In this study, a range of parameters was investigated to identify their use in differentiating patients that will develop a shrinking AAA from those with a stable AAA one-year after EVAR. Hundred-seventy-four patients (67 shrinking AAA, 107 stable AAA) who underwent elective, infrarenal EVAR were enrolled between 2011–2018. Long-term survival was significantly better in patients with a shrinking AAA, compared to those with a stable AAA (<i>p</i> = 0.038). Larger preoperative maximum AAA diameter was associated with an increased likelihood of developing AAA shrinkage one-year after EVAR—whereas older age and larger preoperative infrarenal β angle were associated with a reduced likelihood of AAA shrinkage. However, this multivariate logistic regression model was only able to correctly identify 66.7% of patients with AAA shrinkage from the total cohort. This is not sufficient for implementation in clinical care, and therefore future research is recommended to dive deeper into AAA anatomy, and explore potential predictors using artificial intelligence and radiomics.https://www.mdpi.com/2077-0383/11/5/1394AAAEVARremodelingshrinkageregressionprediction |
| spellingShingle | Rianne E. van Rijswijk Erik Groot Jebbink Suzanne Holewijn Nicky Stoop Steven M. van Sterkenburg Michel M. P. J. Reijnen Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair Journal of Clinical Medicine AAA EVAR remodeling shrinkage regression prediction |
| title | Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair |
| title_full | Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair |
| title_fullStr | Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair |
| title_full_unstemmed | Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair |
| title_short | Predictors of Abdominal Aortic Aneurysm Shrinkage after Endovascular Repair |
| title_sort | predictors of abdominal aortic aneurysm shrinkage after endovascular repair |
| topic | AAA EVAR remodeling shrinkage regression prediction |
| url | https://www.mdpi.com/2077-0383/11/5/1394 |
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