IMP-68, a Novel IMP-Type Metallo-β-Lactamase in Imipenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>

IMP-68, a Novel IMP-Type Metallo-β-Lactamase in Imipenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>

ABSTRACT We recently detected a novel variant of an IMP-type metallo-β-lactamase gene (blaIMP-68) from meropenem-resistant but imipenem-susceptible Klebsiella pneumoniae TA6363 isolated in Tokyo, Japan. blaIMP-68 encodes a Ser262Gly point mutant of IMP-11, and transformation experiments showed that...

Celý popis

Podrobná bibliografie
Hlavní autoři: Hiroaki Kubota, Yasunori Suzuki, Rumi Okuno, Yumi Uchitani, Tsukasa Ariyoshi, Nobuyuki Takemura, Fuminori Mihara, Kazuhisa Mezaki, Norio Ohmagari, Mari Matsui, Satowa Suzuki, Tsuyoshi Sekizuka, Makoto Kuroda, Keiko Yokoyama, Kenji Sadamasu
Médium: Článek
Jazyk:English
Vydáno: American Society for Microbiology 2019-10-01
Edice:mSphere
Témata:
Enterobacteriaceae
Klebsiella
antibiotic resistance
carbapenems
enzyme kinetics
genome analysis
On-line přístup:https://journals.asm.org/doi/10.1128/mSphere.00736-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00736-19

Podobné jednotky