Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II)
Cimetidine is an important hydrogen histamine receptor and can coordinate metal ions in blood plasma. The stability of cimetidine and its complexes with Mn(II), Co(II) and Ni(II) was evaluated by studies of thermogravimetry (TG) and differential thermal analysis (DTA). Cimetidine was thermally stabl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Londrina
2014-02-01
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| Series: | Semina: Ciências Exatas e Tecnológicas |
| Subjects: | |
| Online Access: | http://www.uel.br/revistas/uel/index.php/semexatas/article/view/14186/13934 |
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| author | Ana Carolina Mendes Hacke Fernanda Moreira Egon Schnitzler Neiva Deliberali Rosso |
| author_facet | Ana Carolina Mendes Hacke Fernanda Moreira Egon Schnitzler Neiva Deliberali Rosso |
| author_sort | Ana Carolina Mendes Hacke |
| collection | DOAJ |
| description | Cimetidine is an important hydrogen histamine receptor and can coordinate metal ions in blood plasma. The stability of cimetidine and its complexes with Mn(II), Co(II) and Ni(II) was evaluated by studies of thermogravimetry (TG) and differential thermal analysis (DTA). Cimetidine was thermally stable up to near 190 °C and above this temperature the thermal decomposition occurred in two stages. Complexes of [Mn(HCm)2]Cl2, [Co(Cm)2]Cl2 and [Ni(Cm)2]Cl2 showed a similar behavior. The pyrolytic decomposition occurred in two stages at temperatures above 250 oC. A residue for each complex was detected at the end of the decomposition process. This probably corresponds to the respective metal oxide. |
| first_indexed | 2024-04-12T09:31:23Z |
| format | Article |
| id | doaj.art-7b660e73ac324d3a83328678ccb9fba9 |
| institution | Directory Open Access Journal |
| issn | 1676-5451 1679-0375 |
| language | English |
| last_indexed | 2024-04-12T09:31:23Z |
| publishDate | 2014-02-01 |
| publisher | Universidade Estadual de Londrina |
| record_format | Article |
| series | Semina: Ciências Exatas e Tecnológicas |
| spelling | doaj.art-7b660e73ac324d3a83328678ccb9fba92022-12-22T03:38:21ZengUniversidade Estadual de LondrinaSemina: Ciências Exatas e Tecnológicas1676-54511679-03752014-02-0134222923610.5433/1679-0375.2013v34n2p229Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II)Ana Carolina Mendes Hacke0Fernanda Moreira1Egon Schnitzler2Neiva Deliberali Rosso3Universidade Estadual de Ponta GrossaUniversidade Estadual de Ponta GrossaUniversidade Estadual de Ponta GrossaUniversidade Estadual de Ponta GrossaCimetidine is an important hydrogen histamine receptor and can coordinate metal ions in blood plasma. The stability of cimetidine and its complexes with Mn(II), Co(II) and Ni(II) was evaluated by studies of thermogravimetry (TG) and differential thermal analysis (DTA). Cimetidine was thermally stable up to near 190 °C and above this temperature the thermal decomposition occurred in two stages. Complexes of [Mn(HCm)2]Cl2, [Co(Cm)2]Cl2 and [Ni(Cm)2]Cl2 showed a similar behavior. The pyrolytic decomposition occurred in two stages at temperatures above 250 oC. A residue for each complex was detected at the end of the decomposition process. This probably corresponds to the respective metal oxide.http://www.uel.br/revistas/uel/index.php/semexatas/article/view/14186/13934CimetidineComplex |
| spellingShingle | Ana Carolina Mendes Hacke Fernanda Moreira Egon Schnitzler Neiva Deliberali Rosso Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II) Semina: Ciências Exatas e Tecnológicas Cimetidine Complex |
| title | Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II) |
| title_full | Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II) |
| title_fullStr | Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II) |
| title_full_unstemmed | Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II) |
| title_short | Thermoanalytical studies of cimetidine and complexes with Mn(II) Co(II) and Ni(II) |
| title_sort | thermoanalytical studies of cimetidine and complexes with mn ii co ii and ni ii |
| topic | Cimetidine Complex |
| url | http://www.uel.br/revistas/uel/index.php/semexatas/article/view/14186/13934 |
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