ACITRETIN IN THE TREATMENT OF GRZYBOWSKI TYPE ERUPTIVE KERATOACANTHOMA

The article describes a  case of successful treatment of multiple eruptive keratoacanthoma of Grzybowski in a 82-year old woman with concomitant advanced heart disease and chronic gastritis. The tumor was diagnosed in 1 of 256 patients with keratoacanthoma who attend our clinic, i.e. in 0,39% kerato...

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Bibliographic Details
Main Authors: Zh. S. Kuntsevich, Yu. V. Molochkova, M. A. Bobrov, A. N. Khlebnikova, S. D. Dibirova
Format: Article
Language:Russian
Published: MONIKI 2016-06-01
Series:Alʹmanah Kliničeskoj Mediciny
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Online Access:https://www.almclinmed.ru/jour/article/view/313
Description
Summary:The article describes a  case of successful treatment of multiple eruptive keratoacanthoma of Grzybowski in a 82-year old woman with concomitant advanced heart disease and chronic gastritis. The tumor was diagnosed in 1 of 256 patients with keratoacanthoma who attend our clinic, i.e. in 0,39% keratoacanthoma cases in general and in 0,96% among atypical keratoacanthomas. HLA-A2 gene characteristic for atypical keratoacanthomas was found in this patient. Acitretin was administered for 3 months at a  daily dose of 20 mg. The treatment resulted in a  full regression of the elements with residual areas of scarry atrophy and/or depigmentation. Flattening of the elements was obvious after 2 weeks. The patient tolerated the treatment well.
ISSN:2072-0505
2587-9294