Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report
Reducing postoperative incisional infection is the main reason to administer postoperative antimicrobials (AMD) after emergency laparotomy in horses, while reducing inflammation and providing analgesia are the reasons to administer anti-inflammatory drugs (AID). The basis for postoperative AMD and A...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/9/10/546 |
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| author | Marco Gandini Anna Cerullo Paolo Franci Gessica Giusto |
| author_facet | Marco Gandini Anna Cerullo Paolo Franci Gessica Giusto |
| author_sort | Marco Gandini |
| collection | DOAJ |
| description | Reducing postoperative incisional infection is the main reason to administer postoperative antimicrobials (AMD) after emergency laparotomy in horses, while reducing inflammation and providing analgesia are the reasons to administer anti-inflammatory drugs (AID). The basis for postoperative AMD and AID administration is empirical and only recently has been questioned. Empirical approaches can be changed, and these changes, along with the description of their outcomes, can help produce appropriate stewardship. The aim of this study is to report the changes in AMD and AID regimens in horses undergoing emergency laparotomy at a referral teaching hospital between 2017 and 2021. Signalment, pathology, surgery, prophylactic AMD and AID administration were obtained from the medical records. Difference in AMD and AID regimens throughout the study period were also reported. In 234 postoperative records considered, ninety-two horses received prophylactic AMD, while 142 received pre-operative antimicrobials only. There was a progressive change in regimens throughout the years, increasing the number of AID molecules used. AMD and AID administration in horses has changed in our practice over the years to modulate therapies according to the postoperative complications that eventually arise. In this study, horses not receiving postoperative routine AMD treatment did not show an increased incidence of complications. |
| first_indexed | 2024-03-09T19:24:02Z |
| format | Article |
| id | doaj.art-7b683bccc6c54ba285cd2ad2e1285061 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-09T19:24:02Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-7b683bccc6c54ba285cd2ad2e12850612023-11-24T03:06:27ZengMDPI AGVeterinary Sciences2306-73812022-10-0191054610.3390/vetsci9100546Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center ReportMarco Gandini0Anna Cerullo1Paolo Franci2Gessica Giusto3Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, ItalyDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, ItalyReducing postoperative incisional infection is the main reason to administer postoperative antimicrobials (AMD) after emergency laparotomy in horses, while reducing inflammation and providing analgesia are the reasons to administer anti-inflammatory drugs (AID). The basis for postoperative AMD and AID administration is empirical and only recently has been questioned. Empirical approaches can be changed, and these changes, along with the description of their outcomes, can help produce appropriate stewardship. The aim of this study is to report the changes in AMD and AID regimens in horses undergoing emergency laparotomy at a referral teaching hospital between 2017 and 2021. Signalment, pathology, surgery, prophylactic AMD and AID administration were obtained from the medical records. Difference in AMD and AID regimens throughout the study period were also reported. In 234 postoperative records considered, ninety-two horses received prophylactic AMD, while 142 received pre-operative antimicrobials only. There was a progressive change in regimens throughout the years, increasing the number of AID molecules used. AMD and AID administration in horses has changed in our practice over the years to modulate therapies according to the postoperative complications that eventually arise. In this study, horses not receiving postoperative routine AMD treatment did not show an increased incidence of complications.https://www.mdpi.com/2306-7381/9/10/546colic surgeryhorseperioperative antimicrobial protocolperioperative anti-inflammatory protocolpostoperative complications |
| spellingShingle | Marco Gandini Anna Cerullo Paolo Franci Gessica Giusto Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report Veterinary Sciences colic surgery horse perioperative antimicrobial protocol perioperative anti-inflammatory protocol postoperative complications |
| title | Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report |
| title_full | Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report |
| title_fullStr | Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report |
| title_full_unstemmed | Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report |
| title_short | Changes in Perioperative Antimicrobial and Anti-Inflammatory Drugs Regimens for Colic Surgery in Horses: A Single Center Report |
| title_sort | changes in perioperative antimicrobial and anti inflammatory drugs regimens for colic surgery in horses a single center report |
| topic | colic surgery horse perioperative antimicrobial protocol perioperative anti-inflammatory protocol postoperative complications |
| url | https://www.mdpi.com/2306-7381/9/10/546 |
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