Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells

Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells

Mouse fibroblast cells overexpressing phosphatidylinositol transfer protein α [PI-TPα; sense PI-TPα (SPIα) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-α-induced apoptosis. The conditioned medium (CM) from SPIα cel...

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Bibliographic Details
Main Authors: Martijn Schenning, Claudia M. van Tiel, Daniëlle van Manen, Jord C. Stam, Barend M. Gadella, Karel W.A. Wirtz, Gerry T. Snoek
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Journal of Lipid Research
Subjects:
cyclooxygenase 2
proliferation
eicosanoids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313183

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