Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review
Propranolol, a β-blocker (BB), is one of the drugs that can be misused for suicide. The clinical manifestations of overdose can range from asymptomatic to neurological symptoms such as seizures and loss of consciousness, cardiac shock, and even death. Herein, we describe 2 cases that were referred t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-09-01
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| Series: | Clinical Medicine Insights: Case Reports |
| Online Access: | https://doi.org/10.1177/11795476221126981 |
| _version_ | 1811179553299628032 |
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| author | Ali Sharifpour Mahdieh Sadeghi Zakaria Zakariaei Mostafa Soleymani |
| author_facet | Ali Sharifpour Mahdieh Sadeghi Zakaria Zakariaei Mostafa Soleymani |
| author_sort | Ali Sharifpour |
| collection | DOAJ |
| description | Propranolol, a β-blocker (BB), is one of the drugs that can be misused for suicide. The clinical manifestations of overdose can range from asymptomatic to neurological symptoms such as seizures and loss of consciousness, cardiac shock, and even death. Herein, we describe 2 cases that were referred to our hospital’s emergency department in northern Iran: The first case was a 37-year-old woman who suffered from a decreased level of consciousness, bradycardia, and hypotension after ingesting 4 g of propranolol tablets. In the second case, a 32-year-old woman was admitted with complete cardiac arrest and a suspected history of ingesting 4.8 g of propranolol pills a few hours before admission. Therefore, the time interval between pill intake and treatment initiation seems to be one of the most important factors in prognosis, in addition to the number and dosage of pills ingested. |
| first_indexed | 2024-04-11T06:36:15Z |
| format | Article |
| id | doaj.art-7b6df6fd57ce4486be2934193ac18da7 |
| institution | Directory Open Access Journal |
| issn | 1179-5476 |
| language | English |
| last_indexed | 2024-04-11T06:36:15Z |
| publishDate | 2022-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Case Reports |
| spelling | doaj.art-7b6df6fd57ce4486be2934193ac18da72022-12-22T04:39:42ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762022-09-011510.1177/11795476221126981Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature ReviewAli Sharifpour0Mahdieh Sadeghi1Zakaria Zakariaei2Mostafa Soleymani3Iranian National Registry Center for Lophomoniasis and Toxoplasmosis, Mazandaran University of Medical Sciences, Sari, IranStudent Research Committee, Mazandaran University of Medical Sciences, Sari, IranToxicology and Forensic Medicine Division, Orthopedic and Antimicrobial Resistance Research Centers, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, IranIranian National Registry Center for Lophomoniasis and Toxoplasmosis, Mazandaran University of Medical Sciences, Sari, IranPropranolol, a β-blocker (BB), is one of the drugs that can be misused for suicide. The clinical manifestations of overdose can range from asymptomatic to neurological symptoms such as seizures and loss of consciousness, cardiac shock, and even death. Herein, we describe 2 cases that were referred to our hospital’s emergency department in northern Iran: The first case was a 37-year-old woman who suffered from a decreased level of consciousness, bradycardia, and hypotension after ingesting 4 g of propranolol tablets. In the second case, a 32-year-old woman was admitted with complete cardiac arrest and a suspected history of ingesting 4.8 g of propranolol pills a few hours before admission. Therefore, the time interval between pill intake and treatment initiation seems to be one of the most important factors in prognosis, in addition to the number and dosage of pills ingested.https://doi.org/10.1177/11795476221126981 |
| spellingShingle | Ali Sharifpour Mahdieh Sadeghi Zakaria Zakariaei Mostafa Soleymani Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review Clinical Medicine Insights: Case Reports |
| title | Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review |
| title_full | Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review |
| title_fullStr | Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review |
| title_full_unstemmed | Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review |
| title_short | Seizures and Irreversible Cardiogenic Shock Following Propranolol Poisoning: Report of 2 Cases and Literature Review |
| title_sort | seizures and irreversible cardiogenic shock following propranolol poisoning report of 2 cases and literature review |
| url | https://doi.org/10.1177/11795476221126981 |
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