The combination of phosphoinositol with inositol suppresses colorectal cancer growth and metastasis by regulating CLDN23/ RhoA /ROCK1 pathway

The combination of phosphoinositol with inositol suppresses colorectal cancer growth and metastasis by regulating CLDN23/ RhoA /ROCK1 pathway

Colorectal cancer is a prevalent malignant tumor, with liver metastases being the primary cause of death. The combination of inositol hexaphosphate (IP6) and inositol (INS) has been shown to inhibit colorectal cancer metastasis. We identified a correlation between CLDN23 expression and the occurrenc...

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Bibliographic Details
Main Authors: Haitao Wang, Chuhui Wang, Ning Yang, Zhen Xu, Yisa Han, Feng Liu, Xin Li, Yang Song
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Functional Foods
Subjects:
Colorectal cancer cells
Claudin23
Metastasis
Inositol hexaphosphate
Inositol
RhoA
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623004711

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