Benchmarking post-GWAS analysis tools in major depression: Challenges and implications

Benchmarking post-GWAS analysis tools in major depression: Challenges and implications

Our knowledge of complex disorders has increased in the last years thanks to the identification of genetic variants (GVs) significantly associated with disease phenotypes by genome-wide association studies (GWAS). However, we do not understand yet how these GVs functionally impact disease pathogenes...

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Bibliographic Details
Main Authors: Judith Pérez-Granado, Janet Piñero, Laura I. Furlong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Genetics
Subjects:
fine-mapping
colocalization
post-GWAS
major depression
eQTLs
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1006903/full

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