CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE
Aim. To evaluate the anemia prevalence and its impact on chronic heart failure (CHF) course.Methods. A total of 228 outpatients (86 women and 196 men, aged 39-85 y.o.) with clinically stable CHF (II-IV functional class according to NYHA) were studied. Anemia was defined by the WHO criteria (hemoglob...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2016-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/866 |
| _version_ | 1797232301141131264 |
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| author | V. N. Larina B. Ya. Bart V. G. Larin |
| author_facet | V. N. Larina B. Ya. Bart V. G. Larin |
| author_sort | V. N. Larina |
| collection | DOAJ |
| description | Aim. To evaluate the anemia prevalence and its impact on chronic heart failure (CHF) course.Methods. A total of 228 outpatients (86 women and 196 men, aged 39-85 y.o.) with clinically stable CHF (II-IV functional class according to NYHA) were studied. Anemia was defined by the WHO criteria (hemoglobin levels <13 g/dl in men and <12 g/dl in women).Results. Anemia was found in 18,8% of CHF patients. In all the cases anemia was mild (hemoglobin levels >9 g/dl). Anemia rate did not differ significantly in patients with reduced (18,5%) and preserve (19,1%) or left ventricle ejection fraction (LV EF) (р=0,743). Anemic and non anemic patients were similar in terms of gender, NYHA functional class, heart rate and LV EF. The rate of anemic patients increased significantly up to 35,8% in creatinine clearance <60ml/min. Anemic patients were older (p<0,001), had longer CHF duration (p=0,014), lower body mass index (p=0,041), had diabetes more often (p=0,004, χ2=8,01) in comparison with non anemic patients. Deficiency of iron, vitamin B12 or folic acid was a reason of anemia in 35,8%, 9,4% and 15,1% of patients, respectively. Anemia reason was not detected in 39,7% of patients.Conclusion. Anemia in patients with CHF is associated with age, impaired renal function, diabetes and high hospitalization rate because of CHF deterioration. |
| first_indexed | 2024-03-08T14:04:05Z |
| format | Article |
| id | doaj.art-7b7d0a150ded40cdbb68241f43cbecb6 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:58:06Z |
| publishDate | 2016-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-7b7d0a150ded40cdbb68241f43cbecb62024-04-01T07:43:30ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-016331131710.20996/1819-6446-2010-6-3-311-317865CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILUREV. N. Larina0B. Ya. Bart1V. G. Larin2Russian State Medical UniversityRussian State Medical UniversityRussian State Medical UniversityAim. To evaluate the anemia prevalence and its impact on chronic heart failure (CHF) course.Methods. A total of 228 outpatients (86 women and 196 men, aged 39-85 y.o.) with clinically stable CHF (II-IV functional class according to NYHA) were studied. Anemia was defined by the WHO criteria (hemoglobin levels <13 g/dl in men and <12 g/dl in women).Results. Anemia was found in 18,8% of CHF patients. In all the cases anemia was mild (hemoglobin levels >9 g/dl). Anemia rate did not differ significantly in patients with reduced (18,5%) and preserve (19,1%) or left ventricle ejection fraction (LV EF) (р=0,743). Anemic and non anemic patients were similar in terms of gender, NYHA functional class, heart rate and LV EF. The rate of anemic patients increased significantly up to 35,8% in creatinine clearance <60ml/min. Anemic patients were older (p<0,001), had longer CHF duration (p=0,014), lower body mass index (p=0,041), had diabetes more often (p=0,004, χ2=8,01) in comparison with non anemic patients. Deficiency of iron, vitamin B12 or folic acid was a reason of anemia in 35,8%, 9,4% and 15,1% of patients, respectively. Anemia reason was not detected in 39,7% of patients.Conclusion. Anemia in patients with CHF is associated with age, impaired renal function, diabetes and high hospitalization rate because of CHF deterioration.https://www.rpcardio.online/jour/article/view/866anemiachronic heart failurerenal functioniron deficitvitamin b12 deficitfolic acid deficit |
| spellingShingle | V. N. Larina B. Ya. Bart V. G. Larin CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE Рациональная фармакотерапия в кардиологии anemia chronic heart failure renal function iron deficit vitamin b12 deficit folic acid deficit |
| title | CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE |
| title_full | CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE |
| title_fullStr | CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE |
| title_full_unstemmed | CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE |
| title_short | CLINICAL SIGNIFICANCE OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE |
| title_sort | clinical significance of anemic syndrome in patients with chronic heart failure |
| topic | anemia chronic heart failure renal function iron deficit vitamin b12 deficit folic acid deficit |
| url | https://www.rpcardio.online/jour/article/view/866 |
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