Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept
The present systematic review and meta-analysis summarized data on habitual intake of oligo-, di-, mono-saccharides and polyols from 71 studies (n = 138,653 subjects) using random-effects model. In the general population, overall habitual intake of total FODMAPs is 19.86 (95 % CI: 18.12, 21.6) g/d....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464623005145 |
| _version_ | 1797356131441442816 |
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| author | Yoghatama Cindya Zanzer Stephan Theis |
| author_facet | Yoghatama Cindya Zanzer Stephan Theis |
| author_sort | Yoghatama Cindya Zanzer |
| collection | DOAJ |
| description | The present systematic review and meta-analysis summarized data on habitual intake of oligo-, di-, mono-saccharides and polyols from 71 studies (n = 138,653 subjects) using random-effects model. In the general population, overall habitual intake of total FODMAPs is 19.86 (95 % CI: 18.12, 21.6) g/d. No differences were observed on habitual intake of individual constituents of designated FODMAPs between healthy and those who are suffering with functional gastrointestinal disease and other GI disorders. Multiple meta-regression adjusted with macronutrient components showed that IBS-SSS score is positively correlated with lactose (R2 = 77.78 %, P = 0.006) and total FODMAPs (R2 = 78.48 %, P = 0.0052), but not other individual constituents of designated FODMAPs e.g. fructans, GOS, and total polyols. Macronutrient components such as fat (in 6 out of 6 models) and carbohydrate (in 5 out of 6 models) were positively associated with IBS-SSS score. Our findings add insight on current knowledge of FODMAPs habitual intake in the general population and showed that individual FODMAPs such as lactose and other macronutrient components (fat and carbohydrate) as a constituent significantly related to symptom severity. |
| first_indexed | 2024-03-08T14:22:18Z |
| format | Article |
| id | doaj.art-7b7d4dac14124271a755e38dce0b0191 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-03-08T14:22:18Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-7b7d4dac14124271a755e38dce0b01912024-01-14T05:37:08ZengElsevierJournal of Functional Foods1756-46462024-01-01112105914Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet conceptYoghatama Cindya Zanzer0Stephan Theis1Corresponding author.; BENEO Institute, c/o BENEO GmbH, Obrigheim/Pfalz, GermanyBENEO Institute, c/o BENEO GmbH, Obrigheim/Pfalz, GermanyThe present systematic review and meta-analysis summarized data on habitual intake of oligo-, di-, mono-saccharides and polyols from 71 studies (n = 138,653 subjects) using random-effects model. In the general population, overall habitual intake of total FODMAPs is 19.86 (95 % CI: 18.12, 21.6) g/d. No differences were observed on habitual intake of individual constituents of designated FODMAPs between healthy and those who are suffering with functional gastrointestinal disease and other GI disorders. Multiple meta-regression adjusted with macronutrient components showed that IBS-SSS score is positively correlated with lactose (R2 = 77.78 %, P = 0.006) and total FODMAPs (R2 = 78.48 %, P = 0.0052), but not other individual constituents of designated FODMAPs e.g. fructans, GOS, and total polyols. Macronutrient components such as fat (in 6 out of 6 models) and carbohydrate (in 5 out of 6 models) were positively associated with IBS-SSS score. Our findings add insight on current knowledge of FODMAPs habitual intake in the general population and showed that individual FODMAPs such as lactose and other macronutrient components (fat and carbohydrate) as a constituent significantly related to symptom severity.http://www.sciencedirect.com/science/article/pii/S1756464623005145Excess fructoseFructansLactoseOligosaccharidesPolyolsFODMAP |
| spellingShingle | Yoghatama Cindya Zanzer Stephan Theis Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept Journal of Functional Foods Excess fructose Fructans Lactose Oligosaccharides Polyols FODMAP |
| title | Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept |
| title_full | Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept |
| title_fullStr | Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept |
| title_full_unstemmed | Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept |
| title_short | Systematic review and meta-analysis of habitual intake of fermentable oligo-, di-, mono- saccharides and polyols in the general population and revisiting the low FODMAP diet concept |
| title_sort | systematic review and meta analysis of habitual intake of fermentable oligo di mono saccharides and polyols in the general population and revisiting the low fodmap diet concept |
| topic | Excess fructose Fructans Lactose Oligosaccharides Polyols FODMAP |
| url | http://www.sciencedirect.com/science/article/pii/S1756464623005145 |
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