| Summary: | Given the development of insects’ resistance and deteriorative ecological environment, the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management. Herein, a novel anthranilic diamides containing 3,5-dichloropyridylpyrazole group were designed and synthesized. Their insecticidal potency was assayed against beet armyworm (Spodoptera exigua). Moreover, the structure-activity relationship of these new compounds was also discussed. Of them, compound 15g exhibited potential insecticidal activity. Because of the excellent efficacy against a series of Lepidoptera and low toxicity to mammals, compound 15g, namely tetrachlorantraniliprole, has been developed and launched into the market as an insecticide.
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