Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole
Given the development of insects’ resistance and deteriorative ecological environment, the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management. Herein, a novel anthranilic diamides containing 3,5-dichloropyridylpyrazole group...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2023-12-01
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| Series: | Advanced Agrochem |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773237123000801 |
| _version_ | 1797235470637203456 |
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| author | Huibin Yang Haibo Yu Yunbo Cong Xuegeng Shi Zhinan Hu Junfeng Wang Yuquan Song Bin Li |
| author_facet | Huibin Yang Haibo Yu Yunbo Cong Xuegeng Shi Zhinan Hu Junfeng Wang Yuquan Song Bin Li |
| author_sort | Huibin Yang |
| collection | DOAJ |
| description | Given the development of insects’ resistance and deteriorative ecological environment, the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management. Herein, a novel anthranilic diamides containing 3,5-dichloropyridylpyrazole group were designed and synthesized. Their insecticidal potency was assayed against beet armyworm (Spodoptera exigua). Moreover, the structure-activity relationship of these new compounds was also discussed. Of them, compound 15g exhibited potential insecticidal activity. Because of the excellent efficacy against a series of Lepidoptera and low toxicity to mammals, compound 15g, namely tetrachlorantraniliprole, has been developed and launched into the market as an insecticide. |
| first_indexed | 2024-04-24T16:48:28Z |
| format | Article |
| id | doaj.art-7b80135c0163462caedf3c9698e8df2e |
| institution | Directory Open Access Journal |
| issn | 2773-2371 |
| language | English |
| last_indexed | 2024-04-24T16:48:28Z |
| publishDate | 2023-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Advanced Agrochem |
| spelling | doaj.art-7b80135c0163462caedf3c9698e8df2e2024-03-29T05:51:44ZengKeAi Communications Co., Ltd.Advanced Agrochem2773-23712023-12-0124371375Anthranilic diamide compounds: Discovery of tetrachlorantraniliproleHuibin Yang0Haibo Yu1Yunbo Cong2Xuegeng Shi3Zhinan Hu4Junfeng Wang5Yuquan Song6Bin Li7State Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaState Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaState Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaState Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaState Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaState Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaState Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaCorresponding author.; State Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Sinochem Agrochemicals Research and Development Co., Ltd, Shenyang, 110021, ChinaGiven the development of insects’ resistance and deteriorative ecological environment, the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management. Herein, a novel anthranilic diamides containing 3,5-dichloropyridylpyrazole group were designed and synthesized. Their insecticidal potency was assayed against beet armyworm (Spodoptera exigua). Moreover, the structure-activity relationship of these new compounds was also discussed. Of them, compound 15g exhibited potential insecticidal activity. Because of the excellent efficacy against a series of Lepidoptera and low toxicity to mammals, compound 15g, namely tetrachlorantraniliprole, has been developed and launched into the market as an insecticide.http://www.sciencedirect.com/science/article/pii/S2773237123000801Anthranilic diamidesTetrachlorantraniliproleSynthesisInsecticidal activity |
| spellingShingle | Huibin Yang Haibo Yu Yunbo Cong Xuegeng Shi Zhinan Hu Junfeng Wang Yuquan Song Bin Li Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole Advanced Agrochem Anthranilic diamides Tetrachlorantraniliprole Synthesis Insecticidal activity |
| title | Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole |
| title_full | Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole |
| title_fullStr | Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole |
| title_full_unstemmed | Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole |
| title_short | Anthranilic diamide compounds: Discovery of tetrachlorantraniliprole |
| title_sort | anthranilic diamide compounds discovery of tetrachlorantraniliprole |
| topic | Anthranilic diamides Tetrachlorantraniliprole Synthesis Insecticidal activity |
| url | http://www.sciencedirect.com/science/article/pii/S2773237123000801 |
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