Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison
Abstract Objective For patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma. Comparative studies between Magnetic Resonance Imaging (MRI) and sonographic pancreas sonography are not yet available. The aim of the study was...
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| Format: | Article |
| Language: | English |
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BMC
2019-03-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-019-4193-4 |
| _version_ | 1818337213938663424 |
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| author | Christopher Kloth Dorit Fabricius Inka Wendlik Stefan Andreas Schmidt Matthias Pfahler Elisabeth Lormes Meinrad Beer Wolfgang Kratzer Julian Schmidberger |
| author_facet | Christopher Kloth Dorit Fabricius Inka Wendlik Stefan Andreas Schmidt Matthias Pfahler Elisabeth Lormes Meinrad Beer Wolfgang Kratzer Julian Schmidberger |
| author_sort | Christopher Kloth |
| collection | DOAJ |
| description | Abstract Objective For patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma. Comparative studies between Magnetic Resonance Imaging (MRI) and sonographic pancreas sonography are not yet available. The aim of the study was to compare MRI, sonography and point-shearwave elastography (pSWE). A total of 19 patients were included (10 male, 9 female; age 29.7 ± 14.3 years) in the study. Ultrasonography with pSWE and contrast enhanced MRI with MRCP were performed. Results Significant differences between measurements of pancreatic body were registered in MRI with 1.4 ± 0.6 cm vs 1.0 ± 0.4 cm in ultrasound (p = 0.049), however not for pancreatic head and tail. In 10/19 patients (52.6%) pancreatic parenchyma did not show in MRI because of complete lipomatous transformation, but could be detected in ultrasound. pSWE-values showed no significant differences between the full and partial fatty transformation in pancreatic head (p = 0.968), body (p = 0.657) and tail (p = 0.840). pSWE-values did not correlate with measured signal intensity in T1w flash (p = 0.930, r = 0.025) and T2w HASTE sequences (p = 0.152, r = − 0.375). In patients with CF ultrasound is superior to MRI for displaying full fibro-fatty parenchymal transformation, pancreatic duct. Ultrasound elastography did not provide additional clinical relevant information. |
| first_indexed | 2024-12-13T14:51:39Z |
| format | Article |
| id | doaj.art-7b80316392764eb9a8c5bba67d27a5c8 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-13T14:51:39Z |
| publishDate | 2019-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-7b80316392764eb9a8c5bba67d27a5c82022-12-21T23:41:20ZengBMCBMC Research Notes1756-05002019-03-011211710.1186/s13104-019-4193-4Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparisonChristopher Kloth0Dorit Fabricius1Inka Wendlik2Stefan Andreas Schmidt3Matthias Pfahler4Elisabeth Lormes5Meinrad Beer6Wolfgang Kratzer7Julian Schmidberger8Department of Diagnostic and Interventional Radiology, University Hospital UlmDepartment of Paediatric and Adolescent Medicine, Ulm University HospitalsDepartment of Diagnostic and Interventional Radiology, University Hospital UlmDepartment of Diagnostic and Interventional Radiology, University Hospital UlmDepartment of Internal Medicine I, University Hospital UlmDepartment of Dermatology and Allergic Diseases, Ulm University HospitalDepartment of Diagnostic and Interventional Radiology, University Hospital UlmDepartment of Internal Medicine I, University Hospital UlmDepartment of Internal Medicine I, University Hospital UlmAbstract Objective For patients with cystic fibrosis, the imaging of the pancreas is of crucial importance for the early detection of pancreatic carcinoma. Comparative studies between Magnetic Resonance Imaging (MRI) and sonographic pancreas sonography are not yet available. The aim of the study was to compare MRI, sonography and point-shearwave elastography (pSWE). A total of 19 patients were included (10 male, 9 female; age 29.7 ± 14.3 years) in the study. Ultrasonography with pSWE and contrast enhanced MRI with MRCP were performed. Results Significant differences between measurements of pancreatic body were registered in MRI with 1.4 ± 0.6 cm vs 1.0 ± 0.4 cm in ultrasound (p = 0.049), however not for pancreatic head and tail. In 10/19 patients (52.6%) pancreatic parenchyma did not show in MRI because of complete lipomatous transformation, but could be detected in ultrasound. pSWE-values showed no significant differences between the full and partial fatty transformation in pancreatic head (p = 0.968), body (p = 0.657) and tail (p = 0.840). pSWE-values did not correlate with measured signal intensity in T1w flash (p = 0.930, r = 0.025) and T2w HASTE sequences (p = 0.152, r = − 0.375). In patients with CF ultrasound is superior to MRI for displaying full fibro-fatty parenchymal transformation, pancreatic duct. Ultrasound elastography did not provide additional clinical relevant information.http://link.springer.com/article/10.1186/s13104-019-4193-4Cystic fibrosisPancreasMRI imagingB-mode sonographyShear wave elastography |
| spellingShingle | Christopher Kloth Dorit Fabricius Inka Wendlik Stefan Andreas Schmidt Matthias Pfahler Elisabeth Lormes Meinrad Beer Wolfgang Kratzer Julian Schmidberger Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison BMC Research Notes Cystic fibrosis Pancreas MRI imaging B-mode sonography Shear wave elastography |
| title | Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison |
| title_full | Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison |
| title_fullStr | Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison |
| title_full_unstemmed | Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison |
| title_short | Diagnostic accuracy of MRI with MRCP and B-Mode-sonography with elastography of the pancreas in patients with cystic fibrosis: a point-to-point comparison |
| title_sort | diagnostic accuracy of mri with mrcp and b mode sonography with elastography of the pancreas in patients with cystic fibrosis a point to point comparison |
| topic | Cystic fibrosis Pancreas MRI imaging B-mode sonography Shear wave elastography |
| url | http://link.springer.com/article/10.1186/s13104-019-4193-4 |
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