Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival

Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival

New, effective treatment strategies for glioblastomas (GBMs), the most malignant and invasive brain tumors in adults, are highly needed. In this study, we investigated the potential of integrin α10β1 as a therapeutic target in GBMs. Expression levels and the role of integrin &#...

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Bibliographic Details
Main Authors: Matilda Munksgaard Thorén, Katarzyna Chmielarska Masoumi, Cecilia Krona, Xiaoli Huang, Soumi Kundu, Linnéa Schmidt, Karin Forsberg-Nilsson, Marcus Floyd Keep, Elisabet Englund, Sven Nelander, Bo Holmqvist, Evy Lundgren-Åkerlund
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
glioblastoma (GBM)
glioma
integrin α10
antibody–drug conjugate (ADC)
saporin
Online Access:https://www.mdpi.com/2072-6694/11/4/587

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