Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
Abstract The rapid spread of the coronavirus disease 2019 pandemic urged immense testing capacities as one cornerstone of infection control. Many institutions opened outpatient SARS-CoV-2 test centers to allow large number of tests in comparatively short time frames. With increasing positive test ra...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-03-01
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| Series: | Antimicrobial Resistance and Infection Control |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13756-021-00920-z |
| _version_ | 1818577097587687424 |
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| author | Thomas Scheier Cyril Shah Michael Huber Hugo Sax Barbara Hasse Huldrych F. Günthard Alexandra Trkola Peter W. Schreiber |
| author_facet | Thomas Scheier Cyril Shah Michael Huber Hugo Sax Barbara Hasse Huldrych F. Günthard Alexandra Trkola Peter W. Schreiber |
| author_sort | Thomas Scheier |
| collection | DOAJ |
| description | Abstract The rapid spread of the coronavirus disease 2019 pandemic urged immense testing capacities as one cornerstone of infection control. Many institutions opened outpatient SARS-CoV-2 test centers to allow large number of tests in comparatively short time frames. With increasing positive test rates, concerns for a possible airborne or droplet contamination of specimens leading to false-positive results were raised. In our experimental series performed in a dedicated SARS-CoV-2 test center, 40 open collection tubes placed for defined time periods in proximity to individuals were found to be SARS-CoV-2 negative. These findings argue against false-positive SARS-CoV-2 results due to droplet or airborne contamination. |
| first_indexed | 2024-12-16T06:24:30Z |
| format | Article |
| id | doaj.art-7b8286c0b2fe4fb0aa6ed631375455bb |
| institution | Directory Open Access Journal |
| issn | 2047-2994 |
| language | English |
| last_indexed | 2024-12-16T06:24:30Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Antimicrobial Resistance and Infection Control |
| spelling | doaj.art-7b8286c0b2fe4fb0aa6ed631375455bb2022-12-21T22:41:03ZengBMCAntimicrobial Resistance and Infection Control2047-29942021-03-011011410.1186/s13756-021-00920-zDo we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test centerThomas Scheier0Cyril Shah1Michael Huber2Hugo Sax3Barbara Hasse4Huldrych F. Günthard5Alexandra Trkola6Peter W. Schreiber7Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of ZurichInstitute of Medical Virology, University of ZurichInstitute of Medical Virology, University of ZurichDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of ZurichDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of ZurichDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of ZurichInstitute of Medical Virology, University of ZurichDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of ZurichAbstract The rapid spread of the coronavirus disease 2019 pandemic urged immense testing capacities as one cornerstone of infection control. Many institutions opened outpatient SARS-CoV-2 test centers to allow large number of tests in comparatively short time frames. With increasing positive test rates, concerns for a possible airborne or droplet contamination of specimens leading to false-positive results were raised. In our experimental series performed in a dedicated SARS-CoV-2 test center, 40 open collection tubes placed for defined time periods in proximity to individuals were found to be SARS-CoV-2 negative. These findings argue against false-positive SARS-CoV-2 results due to droplet or airborne contamination.https://doi.org/10.1186/s13756-021-00920-zSARS-CoV-2COVID-19False-positive test resultsContamination |
| spellingShingle | Thomas Scheier Cyril Shah Michael Huber Hugo Sax Barbara Hasse Huldrych F. Günthard Alexandra Trkola Peter W. Schreiber Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center Antimicrobial Resistance and Infection Control SARS-CoV-2 COVID-19 False-positive test results Contamination |
| title | Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center |
| title_full | Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center |
| title_fullStr | Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center |
| title_full_unstemmed | Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center |
| title_short | Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center |
| title_sort | do we cause false positives an experimental series on droplet or airborne sars cov 2 contamination of sampling tubes during swab collection in a test center |
| topic | SARS-CoV-2 COVID-19 False-positive test results Contamination |
| url | https://doi.org/10.1186/s13756-021-00920-z |
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