The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006
<p>Abstract</p> <p>Background</p> <p>Malaria is the direct cause of approximately one million deaths worldwide each year, though it is both preventable and curable. Increasing the understanding of the transmission dynamics of falciparum and vivax malaria and their relat...
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Format: | Article |
Language: | English |
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BMC
2009-06-01
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Series: | Malaria Journal |
Online Access: | http://www.malariajournal.com/content/8/1/142 |
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author | Chowell Gerardo Munayco Cesar V Escalante Ananias A McKenzie F Ellis |
author_facet | Chowell Gerardo Munayco Cesar V Escalante Ananias A McKenzie F Ellis |
author_sort | Chowell Gerardo |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>Malaria is the direct cause of approximately one million deaths worldwide each year, though it is both preventable and curable. Increasing the understanding of the transmission dynamics of falciparum and vivax malaria and their relationship could suggest improvements for malaria control efforts. Here the weekly number of malaria cases due to <it>Plasmodium falciparum </it>(1994–2006) and <it>Plasmodium vivax </it>(1999–2006) in Perú at different spatial scales in conjunction with associated demographic, geographic and climatological data are analysed.</p> <p>Methods</p> <p>Malaria periodicity patterns were analysed through wavelet spectral analysis, studied patterns of persistence as a function of community size and assessed spatial heterogeneity via the Lorenz curve and the summary Gini index.</p> <p>Results</p> <p>Wavelet time series analyses identified annual cycles in the incidence of both malaria species as the dominant pattern. However, significant spatial heterogeneity was observed across jungle, mountain and coastal regions with slightly higher levels of spatial heterogeneity for <it>P. vivax </it>than <it>P. falciparum</it>. While the incidence of <it>P. falciparum </it>has been declining in recent years across geographic regions, <it>P. vivax </it>incidence has remained relatively steady in jungle and mountain regions with a slight decline in coastal regions. Factors that may be contributing to this decline are discussed. The time series of both malaria species were significantly synchronized in coastal (ρ = 0.9, P < 0.0001) and jungle regions (ρ = 0.76, P < 0.0001) but not in mountain regions. Community size was significantly associated with malaria persistence due to both species in jungle regions, but not in coastal and mountain regions.</p> <p>Conclusion</p> <p>Overall, findings highlight the importance of highly refined spatial and temporal data on malaria incidence together with demographic and geographic information in improving the understanding of malaria persistence patterns associated with multiple malaria species in human populations, impact of interventions, detection of heterogeneity and generation of hypotheses.</p> |
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format | Article |
id | doaj.art-7b84259514d64b26b5029f61a1ce61d0 |
institution | Directory Open Access Journal |
issn | 1475-2875 |
language | English |
last_indexed | 2024-04-14T03:29:11Z |
publishDate | 2009-06-01 |
publisher | BMC |
record_format | Article |
series | Malaria Journal |
spelling | doaj.art-7b84259514d64b26b5029f61a1ce61d02022-12-22T02:15:01ZengBMCMalaria Journal1475-28752009-06-018114210.1186/1475-2875-8-142The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006Chowell GerardoMunayco Cesar VEscalante Ananias AMcKenzie F Ellis<p>Abstract</p> <p>Background</p> <p>Malaria is the direct cause of approximately one million deaths worldwide each year, though it is both preventable and curable. Increasing the understanding of the transmission dynamics of falciparum and vivax malaria and their relationship could suggest improvements for malaria control efforts. Here the weekly number of malaria cases due to <it>Plasmodium falciparum </it>(1994–2006) and <it>Plasmodium vivax </it>(1999–2006) in Perú at different spatial scales in conjunction with associated demographic, geographic and climatological data are analysed.</p> <p>Methods</p> <p>Malaria periodicity patterns were analysed through wavelet spectral analysis, studied patterns of persistence as a function of community size and assessed spatial heterogeneity via the Lorenz curve and the summary Gini index.</p> <p>Results</p> <p>Wavelet time series analyses identified annual cycles in the incidence of both malaria species as the dominant pattern. However, significant spatial heterogeneity was observed across jungle, mountain and coastal regions with slightly higher levels of spatial heterogeneity for <it>P. vivax </it>than <it>P. falciparum</it>. While the incidence of <it>P. falciparum </it>has been declining in recent years across geographic regions, <it>P. vivax </it>incidence has remained relatively steady in jungle and mountain regions with a slight decline in coastal regions. Factors that may be contributing to this decline are discussed. The time series of both malaria species were significantly synchronized in coastal (ρ = 0.9, P < 0.0001) and jungle regions (ρ = 0.76, P < 0.0001) but not in mountain regions. Community size was significantly associated with malaria persistence due to both species in jungle regions, but not in coastal and mountain regions.</p> <p>Conclusion</p> <p>Overall, findings highlight the importance of highly refined spatial and temporal data on malaria incidence together with demographic and geographic information in improving the understanding of malaria persistence patterns associated with multiple malaria species in human populations, impact of interventions, detection of heterogeneity and generation of hypotheses.</p>http://www.malariajournal.com/content/8/1/142 |
spellingShingle | Chowell Gerardo Munayco Cesar V Escalante Ananias A McKenzie F Ellis The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006 Malaria Journal |
title | The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006 |
title_full | The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006 |
title_fullStr | The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006 |
title_full_unstemmed | The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006 |
title_short | The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994–2006 |
title_sort | spatial and temporal patterns of falciparum and vivax malaria in peru 1994 2006 |
url | http://www.malariajournal.com/content/8/1/142 |
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