Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media
The utilization of biomaterials as novel carrier materials for lipase immobilization has been investigated by many research groups over recent years. Biomaterials such as agarose, starch, chitin, chitosan, cellulose, and their derivatives have been extensively studied since they are non-toxic materi...
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| Format: | Article |
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MDPI AG
2020-06-01
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| Series: | Catalysts |
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| Online Access: | https://www.mdpi.com/2073-4344/10/6/697 |
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| author | Robson Carlos Alnoch Leandro Alves dos Santos Janaina Marques de Almeida Nadia Krieger Cesar Mateo |
| author_facet | Robson Carlos Alnoch Leandro Alves dos Santos Janaina Marques de Almeida Nadia Krieger Cesar Mateo |
| author_sort | Robson Carlos Alnoch |
| collection | DOAJ |
| description | The utilization of biomaterials as novel carrier materials for lipase immobilization has been investigated by many research groups over recent years. Biomaterials such as agarose, starch, chitin, chitosan, cellulose, and their derivatives have been extensively studied since they are non-toxic materials, can be obtained from a wide range of sources and are easy to modify, due to the high variety of functional groups on their surfaces. However, although many lipases have been immobilized on biomaterials and have shown potential for application in biocatalysis, special features are required when the biocatalyst is used in non-conventional media, for example, in organic solvents, which are required for most reactions in organic synthesis. In this article, we discuss the use of biomaterials for lipase immobilization, highlighting recent developments in the synthesis and functionalization of biomaterials using different methods. Examples of effective strategies designed to result in improved activity and stability and drawbacks of the different immobilization protocols are discussed. Furthermore, the versatility of different biocatalysts for the production of compounds of interest in organic synthesis is also described. |
| first_indexed | 2024-03-10T19:00:18Z |
| format | Article |
| id | doaj.art-7b909e2af6114d90a1cea14dda640552 |
| institution | Directory Open Access Journal |
| issn | 2073-4344 |
| language | English |
| last_indexed | 2024-03-10T19:00:18Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
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| series | Catalysts |
| spelling | doaj.art-7b909e2af6114d90a1cea14dda6405522023-11-20T04:28:36ZengMDPI AGCatalysts2073-43442020-06-0110669710.3390/catal10060697Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional MediaRobson Carlos Alnoch0Leandro Alves dos Santos1Janaina Marques de Almeida2Nadia Krieger3Cesar Mateo4Departamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-900, São Paulo, BrazilDepartamento de Química, Universidade Federal do Paraná, Cx. P. 19061, Centro Politécnico, Curitiba 81531-980, Paraná, BrazilDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, Cx. P. 19081, Centro Politécnico, Curitiba 81531-980, Paraná, BrazilDepartamento de Química, Universidade Federal do Paraná, Cx. P. 19061, Centro Politécnico, Curitiba 81531-980, Paraná, BrazilDepartamento de Biocatálisis, Instituto de Catálisis y Petroleoquímica (CSIC), Marie Curie 2, Cantoblanco, Campus UAM, 28049 Madrid, SpainThe utilization of biomaterials as novel carrier materials for lipase immobilization has been investigated by many research groups over recent years. Biomaterials such as agarose, starch, chitin, chitosan, cellulose, and their derivatives have been extensively studied since they are non-toxic materials, can be obtained from a wide range of sources and are easy to modify, due to the high variety of functional groups on their surfaces. However, although many lipases have been immobilized on biomaterials and have shown potential for application in biocatalysis, special features are required when the biocatalyst is used in non-conventional media, for example, in organic solvents, which are required for most reactions in organic synthesis. In this article, we discuss the use of biomaterials for lipase immobilization, highlighting recent developments in the synthesis and functionalization of biomaterials using different methods. Examples of effective strategies designed to result in improved activity and stability and drawbacks of the different immobilization protocols are discussed. Furthermore, the versatility of different biocatalysts for the production of compounds of interest in organic synthesis is also described.https://www.mdpi.com/2073-4344/10/6/697biomaterialsimmobilizationlipasesbiocatalysisnon-conventional media |
| spellingShingle | Robson Carlos Alnoch Leandro Alves dos Santos Janaina Marques de Almeida Nadia Krieger Cesar Mateo Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media Catalysts biomaterials immobilization lipases biocatalysis non-conventional media |
| title | Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media |
| title_full | Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media |
| title_fullStr | Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media |
| title_full_unstemmed | Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media |
| title_short | Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media |
| title_sort | recent trends in biomaterials for immobilization of lipases for application in non conventional media |
| topic | biomaterials immobilization lipases biocatalysis non-conventional media |
| url | https://www.mdpi.com/2073-4344/10/6/697 |
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