Dual and multi-drug delivery nanoparticles towards neuronal survival and synaptic repair

Dual and multi-drug delivery nanoparticles towards neuronal survival and synaptic repair

Among the macromolecular drug targets in neurodegenerative disorders, the neurotrophin brain-derived neurotrophic factor (BDNF) and its high-affinity tropomyosin-related kinase receptor (TrkB) present strong interest for nanomedicine development aiming at neuronal and synaptic repair. Currently, BDN...

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Bibliographic Details
Main Authors: Angelina Angelova, Borislav Angelov
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
BDNF delivery; neuroprotective lipid nanocarriers; neurotrophic factor; CREB; nanomedicine; macromolecular drugs; combination therapy
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=6;spage=886;epage=889;aulast=Angelova

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