A Conserved Deubiquitinating Enzyme Controls Cell Growth by Regulating RNA Polymerase I Stability

Eukaryotic ribosome biogenesis requires hundreds of trans-acting factors and dozens of RNAs. Although most factors required for ribosome biogenesis have been identified, little is known about their regulation. Here, we reveal that the yeast deubiquitinating enzyme Ubp10 is localized to the nucleolus...

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Bibliographic Details
Main Authors: Lauren A. Richardson, Benjamin J. Reed, J. Michael Charette, Emily F. Freed, Eric K. Fredrickson, Melissa N. Locke, Susan J. Baserga, Richard G. Gardner
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712002197