A Conserved Deubiquitinating Enzyme Controls Cell Growth by Regulating RNA Polymerase I Stability
Eukaryotic ribosome biogenesis requires hundreds of trans-acting factors and dozens of RNAs. Although most factors required for ribosome biogenesis have been identified, little is known about their regulation. Here, we reveal that the yeast deubiquitinating enzyme Ubp10 is localized to the nucleolus...
Main Authors: | Lauren A. Richardson, Benjamin J. Reed, J. Michael Charette, Emily F. Freed, Eric K. Fredrickson, Melissa N. Locke, Susan J. Baserga, Richard G. Gardner |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-08-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124712002197 |
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