Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses

Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses

Lipid oxidation is implicated in a wide range of pathophysiogical disorders, and leads to reactive compounds such as fatty aldehydes, of which the most well known is 4-hydroxy-2E-nonenal (4-HNE) issued from 15-hydroperoxyeicosatetraenoic acid (15-HpETE), an arachidonic acid (AA) product. In addition...

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Bibliographic Details
Main Authors: Sandrine Bacot, Nathalie Bernoud-Hubac, Naïma Baddas, Bernard Chantegrel, Christian Deshayes, Alain Doutheau, Michel Lagarde, Michel Guichardant
Format: Article
Language:English
Published: Elsevier 2003-05-01
Series:Journal of Lipid Research
Subjects:
4-hydroxydodeca-(2E,6Z)-dienal
4-hydroxy-2E-hexenal
4-hydroxy-2E-nonenal
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520311378

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