A CONVENIENT SYNTHESIS OF 5-ARYLIDENE MELDRUM'S ACID DERIVATIVES VIA KNOEVENGAL CONDENSATION WITH VARIOUS FUNCTIONAL GROUPS

A CONVENIENT SYNTHESIS OF 5-ARYLIDENE MELDRUM'S ACID DERIVATIVES VIA KNOEVENGAL CONDENSATION WITH VARIOUS FUNCTIONAL GROUPS

A series of ten arylidene Meldrum’s acid derivatives have been synthesized in excellent yield via Knoevenagel condensation. This efficient synthetic method does not require catalyst and further purification step. Isopropylidene malonate (2,2-dimethyl-1,3-dioxane-4,6-dione), also known as Meldrum’s a...

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Bibliographic Details
Main Authors: Adryana Izzati Adnan, Noor Hidayah Pungot, Nur Ain Nabilah Ash’ari
Format: Article
Language:English
Published: Universiti Teknologi MARA, Negeri Sembilan 2021-04-01
Series:Journal of Academia
Subjects:
biological activities
knoevenagel condensation
meldrum’s acid
nmr spectroscopy
one-pot reaction
Online Access:https://myjms.mohe.gov.my/index.php/joa/article/view/11132

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