Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells
The expression of СOX-2, VEGF, VEGFR-1, VEGFR-2, VEGFR-3, EGFR, endoglin (СD105), and IL-6 was analyzed in the human breast tumor cells having a varying metastatic potential. The role of these factors in the regulation of the metastatic potential of breast cancer cells, as well as that of COX-2 in t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2014-07-01
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| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/4 |
| _version_ | 1826557345078968320 |
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| author | M. A. Taipov Z. N. Nikiforova I. A. Kudryavtsev N. Ye. Arnotskaya V. Ye. Shevchenko |
| author_facet | M. A. Taipov Z. N. Nikiforova I. A. Kudryavtsev N. Ye. Arnotskaya V. Ye. Shevchenko |
| author_sort | M. A. Taipov |
| collection | DOAJ |
| description | The expression of СOX-2, VEGF, VEGFR-1, VEGFR-2, VEGFR-3, EGFR, endoglin (СD105), and IL-6 was analyzed in the human breast tumor cells having a varying metastatic potential. The role of these factors in the regulation of the metastatic potential of breast cancer cells, as well as that of COX-2 in the regulation of metastatic processes at the cellular level were examined. The potential capacity of human breast tumor cells to elaborate factors that stimulate tumor growth, angiogenesis, and metastasis was evaluated. |
| first_indexed | 2024-04-10T01:57:40Z |
| format | Article |
| id | doaj.art-7b9639f9facc474699651d72d2cd6ab9 |
| institution | Directory Open Access Journal |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| last_indexed | 2025-03-14T08:27:07Z |
| publishDate | 2014-07-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj.art-7b9639f9facc474699651d72d2cd6ab92025-03-02T13:05:27ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-010181410.17650/1994-4098-2014-0-1-8-1419Role of COX-2 in the regulation of the metastatic potential of human breast tumor cellsM. A. Taipov0Z. N. Nikiforova1I. A. Kudryavtsev2N. Ye. Arnotskaya3V. Ye. Shevchenko4N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowThe expression of СOX-2, VEGF, VEGFR-1, VEGFR-2, VEGFR-3, EGFR, endoglin (СD105), and IL-6 was analyzed in the human breast tumor cells having a varying metastatic potential. The role of these factors in the regulation of the metastatic potential of breast cancer cells, as well as that of COX-2 in the regulation of metastatic processes at the cellular level were examined. The potential capacity of human breast tumor cells to elaborate factors that stimulate tumor growth, angiogenesis, and metastasis was evaluated.https://ojrs.abvpress.ru/ojrs/article/view/4breast cancercox-2vegfvegfr-1vegfr-2vegfr-3egfrendoglin (сd105)il-6angiogenesismetastasismcf-7bt-474and zr-75-1 human breast tumor cell linestherapeutic targets |
| spellingShingle | M. A. Taipov Z. N. Nikiforova I. A. Kudryavtsev N. Ye. Arnotskaya V. Ye. Shevchenko Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells Опухоли женской репродуктивной системы breast cancer cox-2 vegf vegfr-1 vegfr-2 vegfr-3 egfr endoglin (сd105) il-6 angiogenesis metastasis mcf-7 bt-474 and zr-75-1 human breast tumor cell lines therapeutic targets |
| title | Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells |
| title_full | Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells |
| title_fullStr | Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells |
| title_full_unstemmed | Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells |
| title_short | Role of COX-2 in the regulation of the metastatic potential of human breast tumor cells |
| title_sort | role of cox 2 in the regulation of the metastatic potential of human breast tumor cells |
| topic | breast cancer cox-2 vegf vegfr-1 vegfr-2 vegfr-3 egfr endoglin (сd105) il-6 angiogenesis metastasis mcf-7 bt-474 and zr-75-1 human breast tumor cell lines therapeutic targets |
| url | https://ojrs.abvpress.ru/ojrs/article/view/4 |
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